Volume 20, Number 1 (Scientific Journal of Hamadan University of Medical Sciences-Spring 2013)                   Sci J Hamadan Univ Med Sci 2013, 20(1): 25-31 | Back to browse issues page


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Borzouei S, Esna Ashari F, Kiani S J, Kaveh M R, Goodarzi M T, Salim Bahrami S A. The Relationship between Serum 25-Hydroxyvitamin D Levels and Metabolic Syndrome. Sci J Hamadan Univ Med Sci . 2013; 20 (1) :25-31
URL: http://sjh.umsha.ac.ir/article-1-149-en.html

Assistant Professor, Department of Internal Medicine-Endocrinology, School of Medicine, Hamadan University of Medical Sciences & Health Services, Hamadan, Iran. , borzoueishiva@umsha.ac.ir
Abstract:   (893 Views)

Introduction & Objective: Metabolic syndrome is one of the main health problems raised around the world and vitamin D deficiency is a possible new risk factor. The aim of this study was to understand this relationship in the Iranian population.

Materials & Methods: This case-control study was done on 186 subjects over 20 years referred to endocrine clinic in the spring and summer of 2011. Clinical and laboratory data were col-lected using questionnaires . After determining the subjects with metabolic syndrome accord-ing to ATP III criteria and the control group ,blood samples of all participants were taken to measure 25-hydroxyvitamin D levels and sent to the laboratory. The collected data were ana-lyzed with statistical software SPSS v.16.0 and Pearson's chi square test.

Results: Comparing vitamin D levels between the healthy individuals and the patients showed significant differences between the two groups (32.6± 16.5 in the control group vs.17.3± 10.7 in the case group). In the patients, those with vitamin D deficiency compared with those with normal levels of vitamin D, had higher levels of BMI and triglycerides and lower levels of HDL cholesterol.

Conclusion: It seems that vitamin D-deficient individuals have a greater chance of having metabolic syndrome. However, prospective studies are needed to prove this relationship.

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Type of Study: Original | Subject: Special

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