The aim of this study was to determine whether there is any different in hCG levels of vaginal fluids from normal pregnant women, women with confirmed PROM and with suspected PROM.

          After irrigating the posterior vaginal fornix with 3 ml of sterile saline and procuring vaginal washing , we measured hCG levels. Samples were analyzed from 38 normal pregnant women , 31 women with confirmed PROM , 28 women with suspected PROM.

          The mean of vaginal fluid hCG levels of normal pregnant women were 11.2 (0.00-98.6) mIu/ml. That of women with PROM was 140.2 (0.5 , 390.1) and that of women with suspected PROM was 21.5 (0.0 , 143.9). Sensivity was 80%, specility 83% , positive predictive value 73.7% , negative predictive
   value 88.1% , using a cut-value 20.

          It was concluded that the hCG level in vaginal fluid is a marker of PROM during third trimester.