Volume 9, Number 3 (Scientific Journal of Hamadan University of Medical Sciences-Autumn 2002)                   Sci J Hamadan Univ Med Sci 2002, 9(3): 0-0 | Back to browse issues page


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A. Karimi A, Nateghian A, Karimi M, Shirvani B. Association of Cardiovascular Complications with Acute Phase Response in Kawasaki Patients . Sci J Hamadan Univ Med Sci . 2002; 9 (3)
URL: http://sjh.umsha.ac.ir/article-1-766-en.html

Abstract:   (600 Views)

          Investigation of risk factors leading to cardiac complications in
   Kawasaki disease is extremely important because coronary vasculitis may
   lead to aneurysmal formation , stenosis and myocardial infarction. Various
   laboratory and clinical parameters have been investigated in order to
   find the predictive parameters and risk factors for such complications.
          In present study we addressed the relationship between intensity of
   acute phase response indicators(ESR, CRP, WBC and Platelet counts)  and
   frequency of cardiovascular complications. 52 admitted children with
   Kawasaki disease were included in this retrospective study. Data regarding
   the intensity of acute phase reactants were recorded and relationships 
   between these markers and frequency of cardiovascular problems were
   analyzed using statistical methods.

          Various cardiovascular abnormalities were demonstrated in 13 cases
   (25%) in whom, there were 11 cases with elevated ESR, 6 cases with positive
   CRP, 2 cases with leukocytosis and 4 cases with thrombocytosis but in
   comparison with non affected group , we didn’t find any significant
   correlation between cardiovascular and intensity of acute phase responses.

          The intensity of acute phase response indicators such as ESR, CRP, WBC
   and Platelet counts can not be regarded as useful predictors for 
   cardiovascular complications of Kawasaki disease.

     
Type of Study: Original | Subject: Special

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