Volume 8, Number 1 (Scientific Journal of Hamadan University of Medical Sciences-Spring 2001)                   Sci J Hamadan Univ Med Sci 2001, 8(1): 0-0 | Back to browse issues page


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Mohammad Alizadeh A H, Mani Kashani K, Sharafi N, Najafian M. Comparative Study of Evaluation of Therapeutic Effects of the Thyme C.W , Savory C.W. Drops and Thyme Mixture C.W. with Ranitidine – Metoclopramide Compound in Functional Dyspepsia. Sci J Hamadan Univ Med Sci . 2001; 8 (1)
URL: http://sjh.umsha.ac.ir/article-1-884-en.html

Abstract:   (988 Views)

Functional dyspepsia found in 25% of the general population and a
   large number of patients referred to the health centers. Treatment of this
   disease with promotility drugs is not effective, and is so expensive too.
   Evaluation of therapeutic effects of the thyme C.W, savory C.W. drops and
   thyme mixture in comparison with ranitidine – metoclopramide compound is
   the aim of this study.

          This is a randomized clinical trial study in 180 patients with dyspepsia
   selected in sequential sampling with similar diet , age group and the same
   smoking habit. They were randomly divided into four therapeutic groups;
   the whole groups except to the fourth group used thyme C.W , savory C.W.
   drops and thyme mixture C.W. with ten drops  in three times a day during a
   month in a double blind method. The fourth group used ranitidine 
   metoclopramide compound during a month with the following orders: 1- One
   tablet ranitidine every 12 hours 2- One tablet metoclopramide every 8 hours.
   It is necessary to be mentioned that biopsy urease test (BUT) and histology for
   evaluation of helicobacter pylori were performed in each group and each
   group was divided in two subgroups that include : HP. Positive and HP.
   Negative.

          This study indicated that C.W. drop , savory C.W. drop , thyme mixture drop
   and ranitidine – metoclopramide compound  caused disappearance of 75%
   ( or more )of symptoms of disease (the complete healing) in 55.6% , 53.3% ,
   42.2% and 42.2% of patients respectively.

          Thyme C.W, and savory C.W. drops had the similar therapeutic effects with
   that of ranitidine metoclopramide compound in the patients with functional
   dyspepsia. Thyme mixture C.W. had a similar therapeutic effect with
   ranitidine – metoclopramide compound. Urease positive patients gave
   more response especially with the thyme C.W. drop group.

     
Type of Study: Original | Subject: Special

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