%0 Journal Article %A Roghani-Dehkordi, Farshad %A Roghani, Mehrdad %A Baluchnejadmojarad, Tourandokht %T Protective Effect of Capsicum Frutescens on Contractile Reactivity of Streptozotocin-Diabetic Rats %J Avicenna Journal of Clinical Medicine %V 12 %N 2 %U http://sjh.umsha.ac.ir/article-1-540-en.html %R %D 2005 %K Pepper, Red, Cardiovascular System, Diabetes Mellitus, Contractile Response, Rats, %X Introduction & Objective : Considering the higher incidence of atherosclerosis and cardiovascular disorders in diabetes mellitus, this study was conducted to evaluate the effect of oral one-month administration of red pepper (Capsicum frutescens) on the contractile reactivity of isolated aorta in diabetic rats. Materials & Methods : For this purpose, male Wistar rats(n=32) were randomly divided into control, pepper-treated control, diabetic, and pepper-treated diabetic groups. For induction of diabetes, streptozotcin (STZ) was intraperitoneally administered (60 mg/Kg). Pepper-treated groups received pepper mixed with standard pelleted food at a weight ratio of 1/15. After one month, contractile reactivity of aortic rings to KCl and noreadrenaline was determined using isolated tissue setup. Results : Serum glucose level showed a significant increase in diabetic group at 2nd and 4th weeks (P %> http://sjh.umsha.ac.ir/article-1-540-en.pdf %P 5-9 %& 5 %! Protective Effect of Capsicum Frutescens on Contractile Reactivity of Streptozotocin-Diabetic Rats %9 Original %L A-10-2-480 %+ %G eng %@ 2588-722X %[ 2005