@ARTICLE{Moazami, author = {Moazami, Farhad and }, title = {The Comparison and Survey of Lidocaine and Fentanyl Effects on Attenuating Cardiovascular Responses after Laryngoscopy and Tracheal Intubation }, volume = {7}, number = {4}, abstract ={Cardiovascular responses include increase in blood pressure and heart rate is a common event after laryngoscopy and tracheal intubation, and it has potentially adverse side effects especially in high risk patients. The cause of cardiovascular responses is stimulation of receptors in autonomic nervous system with plasma increase in noradrenalin and other catecholamines. Sometimes this response is in from of parasympathic and vagus nerve stimulation and lead to bradycardia especially in children . The purpose of this study is comparison and survey of lidocaine and fentanyl effects on prevention or attenuating cardiovascular responses after laryngoscopy and tracheal intubation in patients who referred to Hamadan hospitals for elective surgery in 1998. We studied a total of 96 patients , ASA class I and II received a balanced anesthesia were randomly divided into three groups. In the induction of anesthesia and before laryngoscopy and tracheal intubation, group 1 received saline 5 ml , group 2 received lidocaine 1.5 mg/kg and group 3 received fentanyl 2 g/kg. Patients and investigator was blinded to it.Blood pressure and heart rate were recorded at following times:before induction , after induction but before laryngoscopy and intubation , and 1,3,5 minutes after intubation.Then the mean of hemodynamic parameters in steps one and two compared with the same parameters in three following steps. Fentanyl effectively blunted the hemodynamic responses to laryngoscopy and tracheal intubation but saline and lidocaine were found to be ineffective in abolish or attenuating these same response. So according to this study fentanyl is more useful adjunct for preventing hemodynamic responses after laryngoscopy and tracheal intubation than lidocaine. }, URL = {http://sjh.umsha.ac.ir/article-1-902-en.html}, eprint = {http://sjh.umsha.ac.ir/article-1-902-en.}, journal = {Avicenna Journal of Clinical Medicine}, doi = {}, year = {2001} }