AU - Khoshraftar, Ebrahim TI - Comparison Between Lidocaine , Fentanyl and Placebo on Hemodynamic Changes after Intratracheal Suction in ICU Patients PT - JOURNAL ARTICLE TA - umsha JN - umsha VO - 9 VI - 4 IP - 4 4099 - http://sjh.umsha.ac.ir/article-1-777-en.html 4100 - http://sjh.umsha.ac.ir/article-1-777-en.pdf SO - umsha 4 ABĀ  - Suction of endotracheal tube in ICU can cause hemodynamic changes. We compare the effect of lidocaine , fentanyl and placebo on reducing hemodynamic changes following suction in ICU patient. Patients were divided into three groups , each containing twenty two patients: A- Lidocaine group receiving 1.5 mg/kg lidocaine intravenously two minutes before suction , B- Fentanyl group receiving 3 mg/kg fentanyl two minutes before suction , C- Placebo receiving distilled water . The total volume of the three substances was raised to 5 cc. Injecting the drugs and suctioning in a standard technique , we recorded mean arterial pressure , pulse rate , arterial oxygen saturation three times : immediately , after three and six minute’s . The recorded information was analyzed. Based on the results , the injection of Lidocaine before suctioning prevented the hemodynamic changes and hypoxemia , which happened after endotracheal suction. Fentanyl caused hypotension and bradycardia , rejecting the previous reported research. Suctioning in the placebos resulted in hypotension , bradycardia and hypoxemia. We can use intravenous lidocaine before endotracheal suction to prevent hemodynamic changes in ICU patients. CP - IRAN IN - LG - eng PB - umsha PG - 0 PT - Original YR - 2003