TY - JOUR T1 - Study Effects of High Acetone Concentrations in Serratia marcescens Strain 13090-1 TT - بررسی اثرات غلظت بالای استن در باکتری سرشیا مارسیسنس سوش 1-13090 JF - umsha JO - umsha VL - 7 IS - 3 UR - http://sjh.umsha.ac.ir/article-1-922-en.html Y1 - 2000 SP - 0 EP - 0 KW - Acetone /Mutagen / Serratia marcescens N2 - Serratia marcescens strain 13090-1was adapted to increasing doses of acetone , when it was grown in B.H.I broth medium; a high acetone concentration affected Serratia growth more and pigment (prodigiosin) production was higher. When the amount of acetone renge from 5000 to 8000 PPM in B.H.I broth at incubation temperature of 28o c. At more than 13000 PPM of acetone, reduction in the number of serratia cells occurred and larger cells,which were not viable were developed at acetone concentration of more than 19000 PPM. The sensitive cells to many antibiotics formed in the high amount of acetone ( 36000 PPM or more ), and these serratia cells cultured in B.H.I medium without acetone , that never converted to prototype one. Therefore that is improving the mutant serratia cells were developed or inactivation of plasmid(s) DNA occurred at high acetone concentration. M3 ER -