TY - JOUR T1 - Determination and Comparison of the Onset Time of Epidural Anesthesia with Lidocaine-Sufentanil and Lidocaine-Bicarbonate TT - مقایسه اثرات تزریق داخل اپیدورال لیدوکائین ـ سوفنتانیل با لیدو کائین ـ بیکربنات بر روی شروع بیحسی اپیدورال JF - umsha JO - umsha VL - 7 IS - 2 UR - http://sjh.umsha.ac.ir/article-1-933-en.html Y1 - 2000 SP - 0 EP - 0 KW - Anestesia KW - Epidural / Bicarbonate / Lidocaine / Sufentanil N2 - This study was performed to determine and compare the onset time of epidural anesthesia between lidocaine - sufentanil and lidocaine - bicarbonate. Eighty - one patients aged 14 - 65 years who underwent surgical procedures under epidural anesthesia were studied in the Hamadan Medical Sciences University Hospitals in 1998. This study was a double blind,clinical trial.The patients were devided randomly to three groups (lidocain-plasebo ,lidocaine-sufentanil and lidocaine-bicarbonate).After performing the method , the obtained information were entered into the questionnaires . Next , all data were analysed by using one way analysis of variance in the statistical software EPI6. The cold sensory time(sympathetic block)in both groups of lidocaine- bicabonate and lidocaine - sufentanil (5.11min.) was shorter than that of the controlled group(10.22min.). Besides ,the pin prick loss time (sensory block) in the lidocaine- bicarbonate(7.92 min.) and lidocaine- sufentanil (7.29min.) groups was shorter than the controlled group (11.88 min. ). Duration of analgesia in the lidocaine - sufentanile’s group was more than the lidocaine - bicarbonate’s and lidocaine - placebo’s group (350.3 min.versus 221.5 min.and 160.6 min.).The three groups didn’t differ significantly with respect to systolic , diastolic and mean arterial pressure and heart rate. Among the narcotic complications , the incidences of pruritus was 3.7% , but other complications such as nausea, vomiting and respiratory depression were not abserved. Consequently , sufentanil can be used in epidural anesthesia ,because it has fast onset of the anesthesia , prolonged duration of analgesis and low incidence of its complications. M3 ER -