Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
Evaluation of Correlation Between QT Dispersion & Ventricular Fibrillation in Patients with Acute Myocardial Infarction in Ekbatan Hospital of Hamadan
0
0
FA
Behshad
Naghsh Tabrizi
Y
Farzad
Emami
N
According to recent researches about the importance of prognostic
value of QT dispersion (QTD) in patients with acute myocardial infarction ,
the present study was performed to assess the relationship between QT
dispersion increment and incidence of ventricular fibrillation in patients
with acute myocardial infarction.
QT dispersion was calculated by caliper in the first 24 hour’s ECG after
acute myocardial infarction in 30 cases of AMI that complicated by
ventricular fibrillation and was compared with 200 cases without
ventricular fibrillation . Also some information about primary or secondary VF
,EF (according to echocardiography) were recorded in check list. The study
was a descriptive , cross - sectional study.
Direct relationship between QT increment and mechanical dysfunction
of left ventricle (EF < 40%) was showed . In patients with primary VF the
mean of QTD was 20 msec more than the patients with secondary VF. In
patients with acute myocardial infarction (AMI) that complicated with VF
the QTD was greater than the patients without VF.
According to above results we can use QTD as a cheap ,easy and
available method for diagnosis of increased incidence of VF in patients with
AMI.
Myocardial Infarction/ QT Dispersion/ Ventricular Fibrillation
http://sjh.umsha.ac.ir/article-1-834-en.html
Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
Screening of Anti HLA Class One Antibodies in the Sera of Pregnant Women and the Variation of Its Titer During Pregnancy
0
0
FA
Minoo
Adib
Y
Mina
Adib
N
Determination of HLA antigens has an extensive application in paternity,
Histocompatibility testing, and disease suseptibility identification. A vast
arrey of different HLA antisera are required for HLA typing. Such antisera can
be obtained from pregnant women, transfused patients, immunized animals
or hybridoma cells, but still the sera of pregnant women is one of the best
sources for producing of HLA antisera. The pregnant women usually form
antibodies to the foreign HLA antigens of the fetus inherited from the father.
Due to the genetic variations among different races and the very high price
of these antibodies it is preferable to obtain these antisera from locally
pregnant women.
In this study, sera of 40 primiparous and 65 multiparous pregnant Iranian
women were screened monthly (for 3 times) againest their husband’s pure
lymphocytes, using the microlymphocytotoxicity method of NIH.
Among the primiparous 2 cases (5%) and among the multiparous
women 9 cases (13.8%) had HLA antibodies in their sera. The titer and score
of antibody were determined monthly in positive samples. The antibodies
had the highest level in the 6th month of pregnancy.
We concluded that the best source and the time to obtain HLA antisera
are multiparous women in the 6th month of pregnancy
HLA Antigens / Immune Sera / Pregnancy
http://sjh.umsha.ac.ir/article-1-835-en.html
Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
Study of the Effects of Mogadon in Treatment of Infantile Spasms
0
0
FA
Mohammad Mahdi
Taghdiri
Y
Among epileptic syndromes the infantile spasms ( west syndrome ) is the
most malignant one and leads to irreparable brain damage, which is
related directly to duration of spasms. The effectiveness of Mogadon
(Nitrazepam) on treatment of infantile spasms was studied for two-years
(1998-2000) at neurologic ward of Mofid children hospital , Tehran , Iran.
This was prospective uncontrolled clinical trial on 30 childs age 2-24
months with infantile spasms. Patients received Mogadon (NZP) 0.5-1
mg/kg/hr in three divided dose with meal, the patients evaluated regard to
complete and relative control of seizure and drug side effects at the end of
2,4 and 6 weeks of therapy.
At the end of six weeks of therapy 63% were seizure free , 26% had
reduced frequency of siezure , and 47% had complete normalization of
tracing EEG.
Because of high-effectiveness , few side effects and low cost the
Mogadon (NZP) could be a drug of choice in treatment of infantile spasms.
Epilepsy – therapy / Infantile Spasm/ Nitrazepam
http://sjh.umsha.ac.ir/article-1-843-en.html
Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
The Study of Triglyceride and Cholesterol Levels (HDL & LDL) in Patients with Ischemic Stroke Admitted in Sina Hospital of Hamadan City During One Year (1999-2000)
0
0
FA
Shahir
Mazaheri
Y
The aim of this study was evaluation of triglyceride and cholesterol levels in
patients with ischemic stroke admitted in neurology ward during one year
(99-2000).Hyperlipidemia is one of the risk factor for atherosclerosis and
ischemic stroke . Several studies have done for evaluation of changes in
triglyceride and cholesterol level (HDL , LDL) in ischemic stroke patients. In the
present investigation , these changes were studied in relation to age, sex and
other risk factors. This study was supposed to answered to this question : Is there
any difference between Iranian patients and patients of other nationalities with
regard to diet , race and cultural backgrounds?
In this descriptive, cross-sectional study, 115 ischemic stroke patients ,
admitted in neurology ward of Sina hospital, during one year, were
selected. After confirming the diagnosis of ischemic stroke , blood samples
were sent to laboratory. Data obtained, was analyzed by EPI6 package.
Fifty four percent of patients were male and 46% were female . The
majority of them were urban resident and half of them came with
hemiplegia. Cholesterol and LDL levels were increased in 58% and 49%,
respectively, and HDL levels were decreased in 60% of patients. Most
increases in cholesterol and LDL levels were seen in patients between 61-70
years age groups. These changes were more frequent in female patients
than in males and more in patients with Hypertension.
This study showed that there are significant changes in the levels of
cholesterol , LDL and HDL, in patients with ischemic stroke. In the studied
population , hypertension and hyperlipidemia (Increased levels of cholesterol
and LDL , decreased of HDL) were the major risk factors for ischemic stroke.
Triglyceride was not shown to have any significant role. we hope that to
perform other studies in larger skills, to evaluate some ambiguous findings.
Cholesterol / Hyperlipidemia / Ischemic Stroke/ Triglyceride
http://sjh.umsha.ac.ir/article-1-844-en.html
Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
A Histopathological Study of Effects of Intraperitoneal Garlic Extract on Liver in Rats
0
0
FA
Mehri
Ghaforian Borojerdnia
Y
In recent years, many investigations have reported the pharmaceutical
effects of garlic such as antibacterial, antihypertension, antithrombotic,
anticarcinogenic and many others. Studies suggest that garlic may has
toxic effects on body tissues. In this study, histopathological effects of garlic
extract on liver tissue in rats were investigated.
The animals were divided into five groups including control group
(received saline) and four experimental groups (received garlic extract, 50,
100, 200 and 400mg/kg intraperitonally for a month). The sections of liver
tissue were stained by H&E method for histopathological examination.
The histopathological examination indicated that administration of low
dose of garlic (50mg/Kg) has little effects on liver tissue in comparison with
the control animals. However, administration of high dose of garlic
(400mg/kg) induce considerable damage on this tissue in comparison to
other groups.
Although the use of garlic is useful for body, the consumption of high
levels of garlic may induce toxic effects on body tissues. Therefore, further
studies are needed before garlic preparations can be used as medicine.
Garlic / Liver – pathology / Rats
http://sjh.umsha.ac.ir/article-1-845-en.html
Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
The Study of Relationship between Activity of Lichen Planus and Civatte Body
0
0
FA
Alireza
Monsef
Y
Mahdi
Pilehvar
N
Abbas
Zamanian
N
Lichen Planus is an inflammatory disorder of skin and mucous
membrane, with approximately unknown etiology and pathogenesis. From
the clinical aspect, the disease is characterized by polygonal, purple, itchy
and plan papules. Pathological changes are various in dermis and
epidermis. One of those, is necrotic Keratinocyte or Civatte Body that seen
in lower layer of epidermis and specially in upper layer of dermis.
This investigation was a three years study of clinical and histopathological
characteristics of Lichen Planus and relationship between response of
Civatte body (Civ-b) and activity of the disease, in Sina hospital of
Hamadan city (1995-98). This study was an analytic cross sectional study,
and was performed by 106 files and microscopic slides of the patients
affected by Lichen Planus.
In this study, results showed that 75.8% of all dermis Civatte Body are in
active phase of disease and this number is 88.2% for epidermis. The
correlation between number of Civatte body and disease activity was
statistically established by Fisher’s exact test (P value < 0.001). On the other
hand, disease activity was also related to intensity of band from infiltration.
Also results confirm that the more Civatte Body in dermis, the more
epidermis Civatte Body.
In this research, it was established that the more Civatte body, the more
activity of Linchen planus and the decrease of Civatte Body shows
decrease activity and relieve of disease.
Civatte Body / Lichen Planus–diagnosis / Lichen Planus–pathology
http://sjh.umsha.ac.ir/article-1-846-en.html
Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
Study of the Parasitic Infections of School Children in Rural Areas of Hamadan
0
0
FA
Masoud
Saidi jam
Y
Seyyed Mahmoud
Sadjjadi
N
A cross sectional study was carried out in order to assess the parasitic
infections of school children in rural areas of Hamadan.
A total of 906 school children , 6 to 15 years old , from 9 villages in
Hamadan were selected randomly for parasite examination. Parasitological
examination of stool and eggs count were carried out by formalin – ether
concentration and modified stoll’s technique , respectively.
The results showed that total prevalence of intestinal parasites were
86%. The highest prevalence of helminthic infections and pathogenic
protozoa were Ascaris Lumbricoides (39.6%) and Giardia Lamblia
(20.5%). Distribution of parasites according to sex was not significantly
different. Mean ± S.D of intensity of Ascaris Lumbricoides was 17235±22008
with maximum 163000 eggs per gram faeces. Mean±S.D of intensity of
Trichuris Trichiura was 1227±3173 with the maximum 25000 eggs per gram
faeces. Mean ± S.D of intensity of Hymenolepis Nana was 4320±7160. The
mean intensity was higher in male than female.
Helminthiasis – epidemiology / Protozoan Infections – epidemiology / Students
http://sjh.umsha.ac.ir/article-1-848-en.html
Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
The Concentration of Fluoride in Drinking Water of Hamadan and Bahar Cities in 1998-99
0
0
FA
Mohammad Reza
Samarghandy
Y
Gholamhosein
Sadri
N
The purpose of this study was measuring concentration of fluoride in
drinking water in Hamadan and Bahar cities, in west of Iran.
By a pilot study sample size for Hamadan and Bahar were estimated
120 and 30, respectively. The results were compared with Iranian Standard.
The results showed that concentration of fluoride in drinking water of
Hamadan and Bahar were 0.198 and 0.6 mg/lit, respectively, which were
less than the standard limit. The Shefe statistical test showed that the
concentrations of fluoride in summer is less than others season and the
difference was statistically significant (P < 0.001 ) .
Finally, it can be concluded that the concentrations of fluoride in
drinking water of Hamadan and Bahar cities are less than the standard
limit, especially in summer. To solve the problem, it is recommended to
inject sodium fluoride in drinking water of Hamadan and Bahar,
particularity in summer.
Fluoride / Water
http://sjh.umsha.ac.ir/article-1-849-en.html
Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
Frequency of Smear Positive Pulmonary Tuberculosis in Prisoners of Central Prison of Hamadan in 1999
0
0
FA
M.
Ansari
Y
H.
Shah Nazari
N
All factors that produce active tuberculosis are present in prisoners.
The over crowded condition of most prisons coupled with HIV infection,
malnutrition and IV drug abusing among prisoners may lead to a substantial
tuberculosis epidemic in the prison system . Between January and March
1999 we carried out an active case finding survey in Hamadan central prison,
Iran, through the WHO tuberculosis control program.
We interviewed prisoners and those with cough of at least 3 weeks’
duration were screened by sputum-smear microscopy. If sputum smear was
negative after 10 days antibiotic administration and after three consecutive
negative smear , prisoner underwent chest radiography.
106 of 1115 prisoners were screened; (all men , mean age 33.2years). 79
prisoners (74.5%) had addiction to opium. The most common route of opium
were inhalation (70 cases), oral (20 cases), inhalation-oral (15 cases) and
parentral (4 cases). Two screened prisoners (1.88%) had pulmonary
tuberculosis with positive smear and were not taking anti tuberculosis drugs
and had addiction to heroin. 67 (53.7%) of 106 screened prisoners
underwent chest radiography. In 2 prisoners the chest radiograph
suggested active tuberculosis, in 2 prisoners hilar lymph node calcification
was seen due to old tuberculosis and in 2 prisoners suggested calcification
and scar of old tuberculosis in pulmonary apices.
As a result, the frequency of smear positive pulmonary tuberculosis in
central prison of Hamadan was significant and must pay attention to it.
Prisoners , Tuberculosis Pulmonary - diagnosis , Tuberculosis Pulmonary - epidemiology
http://sjh.umsha.ac.ir/article-1-851-en.html
Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
Goiter Survey and Urinary Iodine Concentration in Schoolchildren Aged 8 to 10 Year of Hamadan Province in 1996
0
0
FA
F.
Azizi
Y
R.
Shaikholeslam
N
M.
Hedayati
N
P.
Mirmiran
N
F.
Tolou
N
H.
Delshad
N
Iodine deficiency disorders (IDD) is a worldwide health problem. Many
parts of the Islamic Republic of Iran had been known as areas of endemic
goiter. IDD was accepted a priority health problem in the country , and a
national IDD council was formed in 1989, under the supervision of the
ministry of health and medical education. One of the main strategies of
national council for IDD control was to provide at least 150 mg of iodine per
day to the entire population through making available iodized salt. This
study was performed to evaluate the national IDD council program in 1996,
in rural and urban areas of Hamadan province.
1300 schoolchildren , aged 8 to 10 year, including 50% girls and 50%
boy, were selected through random sampling. Grading of goiter was
performed according to WHO’s classification. Serum T3, T4 and TSH were
measured by RIA and urinary iodine by digestion method.
The mean of serum T3, T4 and TSH were: 9.6±2.0 mg/dl , 165±3 ng/dl and
1.7±0.7 mIu/ml respectively. There were no differences between males and
females and schoolchildren of rural or urban areas. Six person had serum T4
more than 12.5 mg/dl. The mean of urinary iodine was 36 mg/dl in entire
population, 89% had urinary iodine more than 10 mg/dl. Only 4% had urinary
iodine less than 5 mg/dl. Total prevalence of goiter was 86% (91% in girls and
78% in boys).
Based on the available data , seven years after generalized use of
iodized salt and 2 years after that more than 50% of population used iodized
salt , urinary iodine excretion is in acceptable limit. However goiter is still
hyperendemic in Hamadan province.
Goiter , Iodine Deficiency Disorders , Urinary Iodine
http://sjh.umsha.ac.ir/article-1-856-en.html
Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
Investigation about the Semnan Clinoptilolite Zeolites Application for Ammonia - Nitrogen Removal from Polluted Waters
0
0
FA
A.R.
Rahmani
Y
A.H.
Mahvi
N
A.R.
Mesdaghi
N
S.
naseri
N
M.
Shariat
N
F.
Vaezi
N
Nitrogen compounds are one of the several materials in the
wastewaters and effluents that have harmful effects in water resources. In
different experiences , Ion Exchange (IE) with Zeolites were used for
removal of Ammonia-nitrogen. The aim of this research was studying the
application of Semnan’s Zeolite for removal of Ammonium in both Batch
and Continous systems .
The Zeolite Clinoptilolite was supplied by Semnan area mines . The
Zeolite was ground and sieves based on U.S. standard mesh number
20 , 30 , 40 and then conditioned by Ammonium Sulfate and Sodium
Chloride solutions respectively .
The test results on conditioned samples in Batch system was showed
that average Ion Exchange capacity for particles with 20 , 30 and 40
mesh were between 6.65 - 16 mg NH4+ / g Zeolite weight .
Forthermore its selectivity for other cations obtained the ranking of K , NH4 ,
Na , Ca , Mg respectivly . In Continous system , total cation exchange
and till breakthrough point capacity obtain 16.31 - 19.5 and 7.61 - 11.23
mg NH4+ / g Zeolite weight . The resultes indicated that high level of
regeneration (95 - 98%) may be achieved with solution of NaCl .
At present time, the most wastewater treatment plant in our country
designed for removal of organic matter and Ammonium remain in
effluent , and the use of Ion Exchange with Clinoptilolite can be led to
economical remove of NH4 + from effluent .
Ammonium/ Clinoptiloite / Ion Exchange / Wastewater Treatment / Zeolite
http://sjh.umsha.ac.ir/article-1-858-en.html
Hamadan University of Medical Sciences
Avicenna Journal of Clinical Medicine
2588-722X
2588-7238
8
3
2001
12
1
The Study of the Incidence Rate of Accident in the Students of Primary Schools in Hamadan District 1998 – 99
0
0
FA
Kh.
Mani Kashani
Y
M.S.
Saba
N
M.H.
Azimian
N
Accidents as the second cause of disabilities, are the health problems
in society that can cause the social, mental and physical disorders and
sometimes lead to death. Students of primary schools at the age of under
12 have been known as the high risk population in accidents. In this study, it
has been attempted an expressive and clear description of incidence rate
of accident is presented in the students studying in Hamadan primary
schools.
This study performed on 35000 students including 17500 female and
17500 male students in primary schools in the region 1 and 2 depended on
Hamadan district. Accident incidence was reported daily through
questionnaire and collected at the end of each month.
According to the results obtained, the incidence of Accident were 1.6%
in the students of primary schools. The most further incidence was in fifth
grade (1.94 %). Accident incidence in urban schools was reported 1.63%
and in rural schools was 1.37%. In fall season the accident incidence was at
the highest rate (0.716%), and the place of accidents were in the schools
(56.1%). Accident incidence was 2.31% in male students and 0.88% in
female ones. Statistical tests showed the significant difference between
accident incidence with sex, educational grades and the season of
accident incidence (P < 0.05). The average of absence in the injured
students was 2.6 days.
This study demonstrated that incidence of accident in students of
primary schools have been low. The boys was in higher risk than the girls
and the most of the accidents was in fifth grade.
Accident / Disasters / Students
http://sjh.umsha.ac.ir/article-1-859-en.html