2024-03-29T13:57:19+03:30 http://sjh.umsha.ac.ir/browse.php?mag_id=70&slc_lang=fa&sid=1
70-1031 2024-03-29 10.1002
Avicenna Journal of Clinical Medicine Avicenna J Clin Med 2588-722X 2588-7238 10.52547/ajcm 1998 5 2 Differential Diagnosis of Chlamydial Pneumonia Agents “ C. pneumonia and C. psittaci ” by PCR Masoud Hajia Cheristopher Storey Two chlamydial species C. pneumonia and C. psittaci have important role in respiratory infections. In this survey a primer pair was designed in order to differentiate these two species in  one step by single PCR. This differentiation was obtained by having specific product length for each one. All experiments confirmed that the product length in these two species were distinguishable.   The test also showed high sensitivity and specifically for both species. Chlamydia pneumonia / Chlamydia psittaci / Polymerase Chain Reaction 1998 9 01 0 0
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Avicenna Journal of Clinical Medicine Avicenna J Clin Med 2588-722X 2588-7238 10.52547/ajcm 1998 5 2 Nasal Carriers Rate of Staphylococcus aureus in Medical and Non-Medical Staff and Their Antibiotic Sensitivity in Hamadan University of Medical Sciences Seyyed Hamid Hashemi Ayoob Aghaii In order to determine the frequency and distribution of nasal carriers of staphylococcus aureus and their antimicrobial resistance in hospital staff, a cross-sectional descriptive study was performed on 126 hospital staff and on 130 non-hospital staff of Hamadan University of Medical Sciences as control group. Speciments of nasal swabs were cultured on blood agar and the isolated coagulase positive staphylococci were tested for antibiotic sensetivity to commonly used antibiotics. The results suggested that the nasal carriers rate of S. aureus was higher in hospital staff than in control group (31.7% against 25.4%). The rate for physicians was 61.1% and it was significantly higher than other hospital staff) nurse, staff nurse, auxiliary). It was also found that there is no significant difference between the prevalence of nasal carriers of S. aureus among the hospital staff in different wards. The factors such as age, sex, and length  of employment did not have a significant effect on carriers rate. All isolated strains were resistant to penicillin. Resistance to cloxacillin was higher in isolated strain from hospital staff in control group (20% against 6%). However, sensitivity to other antimicrobial agents was high. Drug Resistance Microbial / Personnel Hospital / Staphylococcus aureus 1998 9 01 0 0
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Avicenna Journal of Clinical Medicine Avicenna J Clin Med 2588-722X 2588-7238 10.52547/ajcm 1998 5 2 The Effects of Citalopram, a 5-HT Re-Uptake Inhibitor, on Passive Avoidance Learning Task in Rat Abdolrahman Sarihi Fereshteh Motamedi Naser Naghdi Ali Rashidi-Pour The role of serotonergic systems in learning processes is even more controversial: For example serotonergic lesion have been reported to facilitate, impair, or have no effect on performance in various learning tasks. There are several possible explanations for these discrepancies; different importance of  confounding activation of different learning processes, different importance of confounding factors, such as anxiety on these tasks, lack of direct effects of serotonergic systems on learning processes and modulatory effects of other neurotransmitter on this system. Therefore we decided to test the effects of citalopram on passive avoidance learning (PAL) task. The experiments were performed on male albino rats (180-220gr). Citalopram was injected interaperitoneally at doses of 0.25, 0.5, 1,2, and 4 mg/kg. Citalopram was injected 30 minutes before training, or immediately after training, or 30 minutes before retrieval test. Control groups received saline. Our results indicate that citalopram has no effect on PAL acquisition but facilitates memory consolidation and retrieval. The maximal facilitatory effect was seen at  doses of 2 mg/kg. Citalopram has no effect on motor activity. Our results suggest that 5-HT has different effects on different steps of learning memory. Citalopram / Learning / Serotonin. 1998 9 01 0 0
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Avicenna Journal of Clinical Medicine Avicenna J Clin Med 2588-722X 2588-7238 10.52547/ajcm 1998 5 2 The Comparison and Survey of Dopram and Meperidine Effects in the Treatment of Postanesthetic Shivering Farhad Moazami Postanesthesia shivering is a common complication occurring after general anesthesia. It has potentially adverse side effects, especially in high risk patients that their increased oxygen consumption is critical. Although the true  cause of shivering is unknown, some believe that shivering is useful and beneficial for the patients, because it increases body temperature. We studied a total of 65 patients, 10-40 years. All of the patients were in physical status I and II and they received a balanced anesthesia. Upon development of significant shivering, patients were randomized into two groups receive either meperidine (0.35 mg/kg) or dopram(1.5mg/kg). After injection it was recorded whether the shivering stopped, and other factors such as HR, RR, BP, Temp (axillary), vomiting and the level of consciousness were documented. Percentage of patients whose shivering stopped was significantly higher among the patients receiving dopram than the other group (94% Vs 80%). On the other hand in patients receiving dopram shivering stopped earlier (22s Vs 42s). respiratory pattern, RR and level of consciousness had significantly better changes after dopram consumption. According to this study for treatment of postanesthesia shivering dopram is more useful than meperidine in most situations. Doxapram / Meperidine / Shivering 1998 9 01 0 0
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Avicenna Journal of Clinical Medicine Avicenna J Clin Med 2588-722X 2588-7238 10.52547/ajcm 1998 5 2 The Study of Alterations of alpha – 1 – Antitrypsin (1-AT) in Serum of Hypothyroid Patients Alireza Kheirollah Mahin Zahraei Alpha-1- Protease inhibitor or a1-Antitrypsin (a1-AT) is an a1-glycoprotein and a small molecule which acts as an extracellular inhibitor of serin proteases. It seems that this molecule protein has a protective role in tissues such as inhibition (inactivation) of elastase, colagenase, etc. a1-AT deficiency is a hereditary disorder which characteristed by reduced a1-AT serum level and may cause emphysema, skin disorders, etc. This study measures alteration of this 27 hypothyroid patients and 30 healthy individuals. T3,T4, TSH was assayed by g-counter and TIC (trypsin inhibitory capacity) by sysnthetic substrate BAEE and using U.V. spectrophotometer. The results showed the TIC in hypothyroid patients was significantly lower than that of healthy individual (1.28U+ 0.148 Vs 1.87 + 0.29 mg/ml). Sina correlation between T3 and TIC for hypothyroid was 0.62, then it should be concluded that trypsin inhibitory capacity and a1-AT concentrration decreased in hypothyroidism and decrease dinsity of dermal elastic fiber. alpha 1-Antitrypsin / Hypothyroid / Trypsin Inhibitors 1998 9 01 0 0
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Avicenna Journal of Clinical Medicine Avicenna J Clin Med 2588-722X 2588-7238 10.52547/ajcm 1998 5 2 The Effect of Cyclosporin in Pemphigus Patients who Are Resistant to Conventional Therapy Nahayat Dashgir Parviz Tousi Pemphigus is a chronic blistering disease and prednisolone is regarded as the treatment of choice for this disease. The doses of prednisolone required are high, and considerable morbidity maybe associated the treatment. Immunosuppressive drugs, particularly azathioprin are frequently used addition to prednisolone, as steroid – sparing agents, although in our experience, these are not always well tolerated, in addition some of the patients are resistant to the conventional immunosuppressive agents. For these mentioned patients cyclosprin therapy would be successful. The mechanism by which cyclosprin exerts its immunosuppressive effect in pemphigus vulgaris is not fully understood. It has been assumed that cyclosporin inhibits production of antibodies to T-cell dependent antigens through its action against CD4 – positive lymphocytes. In this study 20 patients with pemphigus who have been resistant to/or complicated with conventional therapy, cyclosporin was added to their regimen. Combined therapy was effective in all patients two. Mortality rate was 10%. No relapse was seen in any patient. Thus according to the results of this the rationale of using cyclosporin is to reduce the dosage of predinsolone there by minimizing its complication and to permit treating of difficult cases. Cyclosporin-therapeutic use / Pemphigus 1998 9 01 0 0
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Avicenna Journal of Clinical Medicine Avicenna J Clin Med 2588-722X 2588-7238 10.52547/ajcm 1998 5 2 A Comparison Study of Heavy Metals in Vegetables, Irrigated by Polluted Water and Healthy Water, in Hamadan City in 1996 Moslem Karim Pour Mohammadreza Samarghandi Gholamhosein Sadri This study was carried out to measure heavy metals in vegetables that irrigated by polluted water in Hamadan farms in 1996. The heavy metals were Pb, Ni, Ca and Cr. These factors were compared with those of the vegetable irrigated by healthy water. 90 samples were chosen randomly in 3 months i.e. 30 samples per month. Data was analyzed using SPSS. The results showed significant differences for Cr and Ni between two groups, P-value were 0.001 and 0.045 respectively. The difference in Cr concentration between two groups was significant in August and October with P-value 0.006 and 0.003 respectively. The mean of Pb concentration was significantly different between two groups in October (P=0.018). Metals / Vegetables / Water 1998 9 01 0 0
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Avicenna Journal of Clinical Medicine Avicenna J Clin Med 2588-722X 2588-7238 10.52547/ajcm 1998 5 2 The Study of 28 Cases of Bochdalek Diaphragmatic Hernia Mohammad Mahdi Taghdiri Mir Mahmoud Sayed Ahadi Hasan Tonekaboni We studied 28 cases of congenital diaphragmatic hernia (CDH) who were admitted to MOFID children hospital from April 1981 up to December 1992. 17 of our patients were male and 11 were female. Our study was focused on Bochdalek hernia and other types of diaphragmatic hernia were excluded. The mortality and morbidity were higher among younger patients. Clinical presentation in neonates was cyanosis and respiratory distress, but in older patients non specific symptoms such as cough, recurrent pneumonia, FUO and FTT were predominant. Post operative complications most commonly noted was sepsis and pneumothorax. Small intestine, spleen and transverse colon were the most common organs herniated. 93% were left sided and 7% right sided. The mean body weight of patients who survived was 3250g, and the mean body weight patients who died after operation was 2750g. 48% of patients were admitted in the first 48h of their life. The mortality rate was 26% and was exclusively seen in newborn. Male / female ratio was 61/39. C.X ray was the most useful paraclinic study in our patients, and we recommend to our colleagues to order C.X ray when they are confronted with an unexplained  respiratory distress and cyanosis. Failure to Thrive / Fever of Unknown Origin / Hernia Diaphragmatic-congenital / Persistent Fetal Circulation Syndrome 1998 9 01 0 0
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Avicenna Journal of Clinical Medicine Avicenna J Clin Med 2588-722X 2588-7238 10.52547/ajcm 1998 5 2 Effect of Different Positions on the Arterial Blood Gas and Vital Sign in CABG Surgery Patients Mahmoud Safari We studied 28 cases of congenital diaphragmatic hernia (CDH) who were admitted to MOFID children hospital from April 1981 up to December 1992. 17 of our patients were male and 11 were female. Our study was focused on Bochdalek hernia and other types of diaphragmatic hernia were excluded. The mortality and morbidity were higher among younger patients. Clinical presentation in neonates was cyanosis and respiratory distress, but in older patients non specific symptoms such as cough, recurrent pneumonia, FUO and FTT were predominant. Post operative complications most commonly noted was sepsis and pneumothorax. Small intestine, spleen and transverse colon were the most common organs herniated. 93% were left sided and 7% right sided. The mean body weight of patients who survived was 3250g, and the mean body weight patients who died after operation was 2750g. 48% of patients were admitted in the first 48h of their life. The mortality rate was 26% and was exclusively seen in newborn. Male / female ratio was 61/39. C.X ray was the most useful paraclinic study in our patients, and we recommend to our colleagues to order C.X ray when they are confronted with an unexplained  respiratory distress and cyanosis. Coronary Artery Bypass / Blood Gas Analysis / Posture 1998 9 01 0 0
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Avicenna Journal of Clinical Medicine Avicenna J Clin Med 2588-722X 2588-7238 10.52547/ajcm 1998 5 2 Timothy Grass as A Foreign Body in the Airways of Children with Clinical Presentation of Pleural Empyema and Lung Abscess Azizollah Abbasi Hasan Nasiri We studied 28 cases of congenital diaphragmatic hernia (CDH) who were admitted to MOFID children hospital from April 1981 up to December 1992. 17 of our patients were male and 11 were female. Our study was focused on Bochdalek hernia and other types of diaphragmatic hernia were excluded. The mortality and morbidity were higher among younger patients. Clinical presentation in neonates was cyanosis and respiratory distress, but in older patients non specific symptoms such as cough, recurrent pneumonia, FUO and FTT were predominant. Post operative complications most commonly noted was sepsis and pneumothorax. Small intestine, spleen and transverse colon were the most common organs herniated. 93% were left sided and 7% right sided. The mean body weight of patients who survived was 3250g, and the mean body weight patients who died after operation was 2750g. 48% of patients were admitted in the first 48h of their life. The mortality rate was 26% and was exclusively seen in newborn. Male / female ratio was 61/39. C.X ray was the most useful paraclinic study in our patients, and we recommend to our colleagues to order C.X ray when they are confronted with an unexplained  respiratory distress and cyanosis. Empyema / Foreign Bodies / Lung Abscess 1998 9 01 0 0