Volume 16, Issue 1 (Scientific Journal of Hamadan University of Medical Sciences-Spring 2009)                   Avicenna J Clin Med 2009, 16(1): 23-27 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Manochehrian N, Hashemi Fesharaki S M, Hajian P, Khoshraftar E. Dextromethorphan Reduces Postoperative Pain of Post Partum Tubal Ligation under General Anesthesia. Avicenna J Clin Med 2009; 16 (1) :23-27
URL: http://sjh.umsha.ac.ir/article-1-329-en.html
1- , manouchehrian@umsha.ac.ir
Abstract:   (4261 Views)

Introduction & Objective: Postoperative pain has harmful effects in many systems. Dextromethorphan reduces postoperative pain in post partum tubal ligation under general anesthesia.

Materials & Methods: In this research 40 patients with ASA class I and II in double blind randomized clinical trial were studied in two groups. 90 minutes before surgery the patients received 90 mg dextromethorphan or placebo (oral). The patients induced general anesthesia with thiopental (5mg/kg), fentanyl 1.5 mg/kg and succinylcholine (1-1.5 mg/kg) and maintenance with halothane and N2O 50%. Patients were observed studied for analgesic requirement, nausea, vomiting, urinary retention and respiratory depression in recovery and 2,4,8 and 24 hours after surgery.

Results: There was no significant difference in age, education, . . . Pain in recovery, 2 and 4 hours after surgery in dextromethorphan was less than placebo group. The analgesic requirement (pethidine) in dextromethophan was less than placebo group.

Conclusion: Administration of 90 mg dextromethorphan 90 minutes before the surgery under GA reduces pain in recovery time , 2 and 4 hours after the surgery.

Full-Text [PDF 149 kb]   (1187 Downloads)    
Type of Study: Original | Subject: Other Clinical Specialties

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Avicenna Journal of Clinical Medicine

Designed & Developed by : Yektaweb