Volume 28, Issue 1 (Avicenna Journal of Clinical Medicine-Spring 2021)
Avicenna J Clin Med 2021, 28(1): 36-41 |
Back to browse issues page
1- Assisstant Professor, Department of Pstchiatry, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
2- Medical Student, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
3- PhD Candidate of Psycholgy, Social Determinants of Health Research Center, Rafsanjan University of medical sciences, Rafsanjan, Iran - Department of Education and Psychology, Kerman Branch, Islamic Azad University, Kerman, Iran
4- Assisstant Professor, Department of Psychiatric Nursing, School of Nursing and Midwifery, Social Determinants of Health Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran ,sayadiahmad@yahoo.com
2- Medical Student, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
3- PhD Candidate of Psycholgy, Social Determinants of Health Research Center, Rafsanjan University of medical sciences, Rafsanjan, Iran - Department of Education and Psychology, Kerman Branch, Islamic Azad University, Kerman, Iran
4- Assisstant Professor, Department of Psychiatric Nursing, School of Nursing and Midwifery, Social Determinants of Health Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran ,
Abstract: (2342 Views)
Background and Objective: Suicide occurs due to a variety of causes, from heredity and biological factors to environmental factors. The present study aimed to evaluate the serum levels of vitamin D, ferritin, and hemoglobin in patients with attempted suicide referring to hospitals and compare them with the control group.
Materials and Methods: A comparison was made between the serum levels of vitamin D, ferritin, and hemoglobin of 60 suicidal patients referring to Ali ibn Abitaleb hospital of Rafsanjan from March to september 2020 and those of 60 relatives of selected patients with no history of suicide. The control group completed the Beck Suicide Thought Questionnaire (BSTQ). Chi-square, ANOVA, independent t-test, Mann-Whitney U test, and Kruskal-Wallis statistical tests were used to analyze the data.
Results: The serum level of vitamin D in Patient with attempted suicide was lower, compared to that in controls (P=0.025). Among the age group of 15-35 years, serum levels of vitamin D were lower than those in the control group (P=0.039). Moreover, serum ferritin level in the attempted suicide group was lower than that in the control group (P=0.003). Serum ferritin level was significantly lower among the suidide attempters aged 15-15 years (P= 0.003), men with attempted suicide (P= 0.003) and suicidal women (P= 0.045), as compared to the control group.
Conclusion: As demonstratedd by the results of the present study, vitamin D deficiency and anemia can be two major risk factors for suicide. Therefore, it is necessary to identify and treat these deficiencies in people with psychological disorders, such as depression.
Materials and Methods: A comparison was made between the serum levels of vitamin D, ferritin, and hemoglobin of 60 suicidal patients referring to Ali ibn Abitaleb hospital of Rafsanjan from March to september 2020 and those of 60 relatives of selected patients with no history of suicide. The control group completed the Beck Suicide Thought Questionnaire (BSTQ). Chi-square, ANOVA, independent t-test, Mann-Whitney U test, and Kruskal-Wallis statistical tests were used to analyze the data.
Results: The serum level of vitamin D in Patient with attempted suicide was lower, compared to that in controls (P=0.025). Among the age group of 15-35 years, serum levels of vitamin D were lower than those in the control group (P=0.039). Moreover, serum ferritin level in the attempted suicide group was lower than that in the control group (P=0.003). Serum ferritin level was significantly lower among the suidide attempters aged 15-15 years (P= 0.003), men with attempted suicide (P= 0.003) and suicidal women (P= 0.045), as compared to the control group.
Conclusion: As demonstratedd by the results of the present study, vitamin D deficiency and anemia can be two major risk factors for suicide. Therefore, it is necessary to identify and treat these deficiencies in people with psychological disorders, such as depression.
Type of Study: Original |
Subject:
Psychiatry
References
1. World Health Organization. Suicide prevention (SUPRE). Genevea: World Health Organization; 2012.
2. Bertolote JM, Fleischmann A. Suicide and psychiatric diagnosis: a worldwide perspective. World Psychiatry. 2002;1(3):181-5. PMID: 16946849
3. Bachmann S. Epidemiology of suicide and the psychiatric perspective. Int J Environ Res Public Health. 2018;15(7):1425
4. Kaplan HI, Sadock BJ. Synopsis of psychiatry, behavioral science and clinical psychiatry. Philadelphia: Lippincott Williams and Wilkins; 2015.
5. Penckofer S, Kouba J, Byrn M, Estwing Ferrans C. Vitamin D and depression: where is all the sunshine? Issues Ment Health Nurs. 2010;31(6):385-93. PMID: 20450340 DOI: 10.3109/01612840903437657
6. de Souza WN, Norde MM, Oki E, Rogero MM, Marchioni DM, Fisberg RM, et al. Association between 25-hydroxyvitamin D and inflammatory biomarker levels in a cross-sectional population-based study, Sao Paulo, Brazil. Nutr Res. 2016;36(1):1-8. PMID: 26773775 DOI: 10.1016/j.nutres.2015.10.006
7. Humble MB. Vitamin D, light and mental health. J Photochem Photobiol B Biol. 2010;101(2):142-9. DOI: 10.1016/j.jphotobiol.2010.08.003
8. Cho CH, Lee HJ. Why Do Mania and suicide occur most often in the spring? Psychiatry Investig. 2018;15(3):232-4. PMID: 29566464 DOI: 10.30773/pi.2017.12.20
9. Yi S, Nanri A, Poudel-Tandukar K, Nonaka D, Matsushita Y, Hori A, et al. Association between serum ferritin concentrations and depressive symptoms in Japanese municipal employees. Psychiatry Res. 2011;189(3):368-72. PMID: 21470691 DOI: 10.1016/j.psychres.2011.03.009
10. Dupont C. Prevalence of iron deficiency. Arch Pediatr. 2017;24(5S):5S45-8. PMID: 28622782 DOI: 10.1016/S0929-693X(17)24009-3
11. HajEbrahimi B, Kazemi AM. Inflammation and depression: mechanisms and involved molecules. J Sabzevar Univ Med Sci. 2013;20(3):380-9.
12. Bargi R, Salmani H, Asgharzadeh Yazdi F, Hosseini M. Inflammation and the brain disorders: a review. Neurosc J Shefaye Khatam. 2017;5(3):68-82. DOI: 10.18869/acadpub.shefa.5.3.68
13. Grudet C, Malm J, Westrin A, Brundin L. Suicidal patients are deficient in vitamin D, associated with a pro-inflammatory status in the blood. Psychoneuroendocrinol. 2014;50:210-9. PMID: 25240206 DOI: 10.1016/j.psyneuen.2014.08.016
14. Haddad Kashani H, Seyed Hosseini E, Nikzad H, Soleimani A, Soleimani M, Tamadon MR, et al. The effects of vitamin D supplementation on signaling pathway of inflammation and oxidative stress in diabetic hemodialysis: a randomized, double-blind, placebo-controlled trial. Front Pharmacol. 2018;9:50. PMID: 29456507 DOI: 10.3389/fphar.2018.00050
15. Baune BT, Neuhauser H, Ellert U, Berger K. The role of the inflammatory markers ferritin, transferrin and fibrinogen in the relationship between major depression and cardiovascular disorders - The German Health Interview and Examination Survey. Acta Psychiatr Scand. 2010;121(2):135-42. PMID: 20073117 DOI: 10.1111/j.1600-0447.2009.01435.x
16. Beck AT, Kovacs M, Weissman A. Assessment of suicidal intention: the Scale for Suicide Ideation. J Consult Clin Psychol. 1979;47(2):343-52. PMID: 469082 DOI: 10.1037//0022-006x.47.2.343
17. Kim SY, Jeon SW, Lim WJ, Oh KS, Shin DW, Cho SJ, et al. Vitamin D deficiency and suicidal ideation: a cross-sectional study of 157,211 healthy adults. J Psychosom Res. 2020;134:110125. PMID: 32388454 DOI: 10.1016/j.jpsychores.2020.110125
18. Park JI, Yang JC, Won Park T, Chung SK. Is serum 25-hydroxyvitamin D associated with depressive symptoms and suicidal ideation in Korean adults? Int J Psychiatry Med. 2016;51(1):31-46. PMID: 26681234 DOI: 10.1177/0091217415621042
19. Fond G, Faugere M, Faget-Agius C, Cermolacce M, Richieri R, Boyer L, et al. Hypovitaminosis D is associated with negative symptoms, suicide risk, agoraphobia, impaired functional remission, and antidepressant consumption in schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2019;269(8):879-86. PMID: 30078128 DOI: 10.1007/s00406-018-0932-0
20. Gokalp G. The association between low vitamin D levels and suicide attempts in adolescents. Ann Clin Psychiatry. 2020;32(2):106-13. PMID: 31990969
21. Grobe M, Kretzschmar G, Vuica A, Filipovic N. Expression of vitamin D receptors in the superior cervical ganglia of rats. Biotech Histochem. 2018;93(5):320-7. PMID: 29954226 DOI: 10.1080/10520295.2018.1425910
22. Anjum I, Jaffery SS, Fayyaz M, Samoo Z, Anjum S. The role of vitamin D in brain health: a mini literature review. Cureus. 2018;10(7):e296. PMID: 30214848 DOI: 10.7759/cureus.2960
23. Faye PA, Poumeaud F, Miressi F, Lia AS, Demiot C, Magy L, et al. Focus on 1,25-dihydroxyvitamin D3 in the peripheral nervous system. Front Neurosci. 2019;13:348. PMID: 31031586 DOI: 10.3389/fnins.2019.00348
24. Eizadi-Mood N, Poornia MR. Role of anemia and related factors in intentional suicidal attempts. J Isfahan Med Sch. 2011;29(132):1-8.
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |