Volume 22, Issue 1 (Scientific Journal of Hamadan University of Medical Sciences-Spring 2015)                   Avicenna J Clin Med 2015, 22(1): 71-75 | Back to browse issues page

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Eshghi G, Khezrian L, Feyzian M. A Comparative Study of Vitamin D Levels in Persons with Hair Loss and Healthy Subjects . Avicenna J Clin Med 2015; 22 (1) :71-75
URL: http://sjh.umsha.ac.ir/article-1-59-en.html
1- , khezrian.leila@yahoo.com
Abstract:   (22300 Views)
Introduction & Objectives: Alopecia or hair loss is defined as the loss of hair on the head or body. Despite the benign prognosis of hair loss, it has a clear impact on the quality of life of the patients who are involved. There are many reasons to explain the pathophysiology of hair loss. Among many nutritional factors, vitamin D deficiency may play a role in hair loss too. Active vitamin D or 1, 25 dihydroxy vitamin D has an effect on the expression of some genes in normal differentiation of epidermal cells and hair follicles. The purpose of this study was to determine the level of vitamin D in patients with hair loss compared with healthy controls.
Materials & Methods: From 2014 to 2015, 70 patients were enrolled in this case-control study. Including 40 women and 30 men, the mean age was 31.2 ± 0.82 years in the case group, 33.8 ± 0.92 years in the control group. Groups were matched by sex, age and season of review. In the both groups, there were 20 women (57.1%) and 15 men (42.5%). After the clinical diagno-sis of hair loss by the physician, patient's blood samples were sent for testing vitamin D levels by kits of a laboratory center. 
Results: Patients, compared with controls, had lower levels of vitamin D and there was signifi-cant relationship between hair loss and low levels of vitamin D (16.188±6.91 vs 20.37±7.47, and P=0.04). Female patients had lower levels of vitamin D, compared with controls and there was significant relationship between hair loss and low levels of vitamin D (14.14±5.8 vs 18.74±7.08 and P=0.03). The group of male patients had lower levels of vitamin D, but in comparison with the control group, no significant relationship was found. 
Conclusion: This study showed that, there is a relationship between vitamin D levels and hair loss in women.
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Type of Study: Original | Subject: Other Clinical Specialties

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