Volume 6, Issue 1 (Scientific Journal of Hamadan University of Medical Sciences-Autumn & Winter 1999)                   Avicenna J Clin Med 1999, 6(1): 0-0 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Jalali M, Golalipour J, Fazel A. Hypervitaminosis A Induced First Arch Syndrome. Avicenna J Clin Med 1999; 6 (1)
URL: http://sjh.umsha.ac.ir/article-1-978-en.html
Abstract:   (4953 Views)

In this study we examine the effect(s) of excess vitamin A on developing first branchial arch. Intraperitoneal administration of 10000 u/Kg of vitamin A at zero and 12 hrs, on day of gestation (vaginal plug = zero) induced high incidences of craniofacial defect such as mandibular hypoplasia and cleft palate. It is well known that distruption among the neural crest cells migration and/or differentiation during face formation might cause facial malformation. Based on our results, we may conclude that excess vitamin A probably interfere with crest cells migration in cranifacial as it may induced excess cell death. The later phenomena may also cause facial defects.

Type of Study: Original | Subject: Other Clinical Specialties

Add your comments about this article : Your username or Email:

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2023 CC BY-NC 4.0 | Avicenna Journal of Clinical Medicine

Designed & Developed by : Yektaweb