One of the most important drug which use in malaria treatment is chloroguine, this drug has schizontocidal effect (except in the cases of plasmodium falciparum resistance to chloroquine). Primaquine had effect on exoerythrocytic stage of malaria parasite and use for radical cure of malaria.

Quinine is a useful drug especially in cerebral malaria treatment. Today antibiotic. Mefloquine , sulfonamide …….are use in the cases of drug resistance falciparum malaria to chloroquine. For chemoprophylaxis in malaria, chloroquine and draprim are useful.