Volume 26, Issue 4 (Avicenna Journal of Clinical Medicine-Winter 2020)                   Avicenna J Clin Med 2020, 26(4): 220-226 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rahimi H, Azizkhani L, Vahedi S, Akhbari K, Ardalani B, Khalafi B. Study of the Duration, Outcomes, and Related Factors of Reperfusion Therapy in Patients with ST-Segment Elevation Myocardial Infarction. Avicenna J Clin Med 2020; 26 (4) :220-226
URL: http://sjh.umsha.ac.ir/article-1-1989-en.html
1- , leila433@gmail.com
Abstract:   (2919 Views)
Background and Objective: One of the most important advancements regarding the care of patients with acute myocardial infarction is the administration of anti-coagulation medicines (e.g., streptokinase). However, it must be noticed that this medicine requires rapid and timely administration. Moreover, Percutaneous Coronary Intervention (PCI) is increasingly used as a method of revascularization. Considering the importance of time for the effective use of these methods, the present study aimed to investigate the duration of the process, treatment outcome, and its associated factors in patients with ST-segment elevation myocardial infarction (STEMI) who were candidates for streptokinase or PCI.
Materials and Methods: The present descriptive-analytical study made use of total population sampling so that all patients with STEMI who did not meet the exclusion criteria were included in the study in 2017. The study population consisted of 183 patients who had referred to the emergency ward of Tohid Hospital in Sanandaj, Iran. The patients were investigated regarding their age, gender, day of admission, pain-to-admission time, the average travel time to the hospital, type of referral, underlying illness, time of myocardial infarction diagnosis, starting time of reperfusion therapy, and final outcome. The collected data were recorded in the designed forms and then entered into SPSS software (version 22). Descriptive statistics formulas (i.e., mean, standard deviation, and percentage) were used regarding research questions. Moreover, regarding the research hypotheses, the chi-square test and correlation coefficients were used in the case of qualitative and quantitative variables, respectively.
Results: According to the results, the majority of patients were male patients over 50 years old with no history of myocardial infarction. A total of 146 (79.8%) and 37 (20.2%) of participants were male and female, respectively. Moreover, the mean age of the participants was 58.52 and 28 of them (15.3%) had a history of myocardial infarction. The mean duration time of ECG and myocardial infarction diagnosis was 4.2 and 18.85 min, respectively. Furthermore, the mean duration time from patient admission to receiving intervention was estimated at 107.68 min. It should also be mentioned that their average length of hospital stay was 4.9 days.
Conclusion: Based on the results, it can be said that the mortality rate was higher in older patients than in others. Moreover, the duration of ECG in female patients was longer in comparison to the male patients. In addition, starting the reperfusion therapy took longer in the night shifts.
Full-Text [PDF 743 kb]   (998 Downloads)    
Type of Study: Original | Subject: Cardiovascular Diseases

1. Marx J, Walls R, Hockberger R. Rosen's emergency medicine-concepts and clinical practice. 8th ed. Philadelphia: Elsevier Health Sciences; 2014. P. 214.
2. Jabbad HH, Elgaby E, Alama MN. Improving door to needle thrombolysis in acute ST-elevation myocardial infarction. Saudi J Internal Med. 2015;5(1):19-23. DOI 10.32790/sjim.2015.5.1.4
3. Puskarich MA, Jones AE. Tintinalli's emergency medicine: a comprehensive study guide. New York: McGraw-Hill Education; 2015. P. 16.
4. Kasper D, Fauci A, Hauser S, Longo D, Jameson J. Harrison's principles of internal medicine. 19th ed. New York: McGraw-Hill; 2015. P. 325, 1595, 1599, 1605.
5. Mohammed O, Paramba FC, Aboobaker NV, Mohammed RA, Purayil NK, Jassim HM, et al. Reduction in door-to-needle time after transfer of thrombolysis site from CCU to emergency department Emerg Med Int. 2013;2013:208271. PMID: 24205437 DOI: 10.1155/2013/208271
6. Mann DL, Zipes DP, Libby P, Bonow RO. Braunwald's heart disease: a textbook of cardiovascular medicine. Philadelphia: Elsevier Health Sciences; 2014. P. 1107.
7. Marjani K, Solaimanpoor M, Allahmoradi Z, Etemadi V, Noori M. Clinical audit duration of streptokinase injection process in patients with myocardial infarction in Tabriz Shahid Mahallati Hospital in 2011-2012. First Conference on Clinical Audit and Quality Improvement, Aliabad-e Katul, Iran; 2018. [In Persian]
8. Mirzaee Poor F, Forood A, Masoomi M, Rashidinejad H, Soroor Azimzadeh B, Ghazanfari A. Assessing time between arriving to hospital and administration of streptokinase in patients with acute myocardial infarction in emergency department of Kerman University of Medical Sciences in 2003-4. J Kerman Univ Med Sci. 2008;15(3):217-23. [In Persian]
9. Rajabi-Moghadam H, Raygan F, Nourddini M, Mousavi SG, Taghadosi M, Zahedi M. Evaluating in-hospital delay for fibrinolytic therapy of myocardial infarction patients with acute ST-elevation in Kashan Shahid-Beheshti hospital during 2007-2010. Feyz. 2012;16(5):468-75. [In Persian]
10. Manouchehrifar M, Ghasemi S., Shojaee M, ShahhosseiniT, Lashgari A. Characteristics of patients with myocardial infarction admitted to the emergency department; a five years epidemiological study. Iran J Emerg Med. 201;3(4):138-42.
11. Rahimzadeh M, Kavehei B. Short-term survival rates after myocardial infractions in Iran: meta-analysis and systematic review. J Arak Univ Med Sci. 2017;20(120):57-67. [In Persian]

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Avicenna Journal of Clinical Medicine

Designed & Developed by : Yektaweb