Volume 32, Issue 4 (Avicenna Journal of Clinical Medicine-Winter 2026)
Avicenna J Clin Med 2026, 32(4): 226-232 |
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Bigdeli A, Karampourian A, Safdari A, Moshki A. Investigation of Changes in Hemoglobin, Hematocrit, Serum Osmolality, and Electrolytes during Transurethral Resection of Prostate. Avicenna J Clin Med 2026; 32 (4) :226-232
URL: http://sjh.umsha.ac.ir/article-1-3277-en.html
URL: http://sjh.umsha.ac.ir/article-1-3277-en.html
1- Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran
2- Department of Health in Emergency and Disaster, School of Health, Hamadan University of Medical Sciences, Hamadan, Iran & Urology and Nephrology Research Center, Avicenna Institute of Clinical Sciences, Hamadan University of Medical Sciences, Hamadan, Iran ,a.karampourian@umsha.ac.ir
3- Department of Nursing, School of Nursing and Midwifery, Semnan University of Medical Sciences, Semnan, Iran
2- Department of Health in Emergency and Disaster, School of Health, Hamadan University of Medical Sciences, Hamadan, Iran & Urology and Nephrology Research Center, Avicenna Institute of Clinical Sciences, Hamadan University of Medical Sciences, Hamadan, Iran ,
3- Department of Nursing, School of Nursing and Midwifery, Semnan University of Medical Sciences, Semnan, Iran
Abstract: (60 Views)
Background and Objective: Benign prostatic hyperplasia (BPH) is one of the most common lower urinary tract disorders in men. Transurethral resection of the prostate (TURP) is a standard treatment modality for this condition. Absorption of irrigation fluid during surgery may lead to hematological and electrolyte disturbances, including TURP syndrome. The present study aimed to precisely investigate changes in these parameters.
Materials and Methods: This descriptive cross-sectional retrospective study collected data through systematic extraction of information recorded in patients' medical records. Initial data were compiled in Excel software, followed by statistical analysis using SPSS version 25. Paired t-test, chi-square, Fisher's exact test, and Mann-Whitney U test were employed for data analysis, with a significance level set at 0.05.
Results: Postoperatively, mean hemoglobin decreased from 13.80 to 12.87 g/dL (P >0.05) and hematocrit from 42.43% to 39.09% (P > 0.05), with these changes being statistically significant. Significant alterations were also observed in serum electrolytes; sodium levels decreased from 139.98 to 139.96 mEq/L (P = 0.003), and potassium levels from 4.37 to 4.11 mEq/L (P> 0.05). Changes in serum osmolality were not statistically significant.
Conclusion: These findings highlight the substantial impact of TURP on patients' hematological and electrolyte parameters and underscore the necessity for meticulous postoperative monitoring of these factors.
Materials and Methods: This descriptive cross-sectional retrospective study collected data through systematic extraction of information recorded in patients' medical records. Initial data were compiled in Excel software, followed by statistical analysis using SPSS version 25. Paired t-test, chi-square, Fisher's exact test, and Mann-Whitney U test were employed for data analysis, with a significance level set at 0.05.
Results: Postoperatively, mean hemoglobin decreased from 13.80 to 12.87 g/dL (P >0.05) and hematocrit from 42.43% to 39.09% (P > 0.05), with these changes being statistically significant. Significant alterations were also observed in serum electrolytes; sodium levels decreased from 139.98 to 139.96 mEq/L (P = 0.003), and potassium levels from 4.37 to 4.11 mEq/L (P> 0.05). Changes in serum osmolality were not statistically significant.
Conclusion: These findings highlight the substantial impact of TURP on patients' hematological and electrolyte parameters and underscore the necessity for meticulous postoperative monitoring of these factors.
Keywords: Hematological Changes, Hemoglobin, Prostatic Hyperplasia, Serum Electrolytes, Transurethral Resection of Prostate
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