Volume 32, Issue 4 (Avicenna Journal of Clinical Medicine-Winter 2026)
Avicenna J Clin Med 2026, 32(4): 233-241 |
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Ariya S, Amerian M, Donyaei A, Khosravi A, Amiri Largani H, Sohrabi M B, et al . Comparison of the Effects of Resistance Exercise with Aerobic Exercise on Parathyroid Hormone and Mineral Metabolism in Hemodialysis Patients. Avicenna J Clin Med 2026; 32 (4) :233-241
URL: http://sjh.umsha.ac.ir/article-1-3279-en.html
URL: http://sjh.umsha.ac.ir/article-1-3279-en.html
Shahin Ariya1 
, Monire Amerian2 , Adel Donyaei3 , Ahmad Khosravi4 , Hossein Amiri Largani5 , Mohammad Bagher Sohrabi6 , Saeed Rashidi1 , Marjan Rashidan6
, Monire Amerian2 , Adel Donyaei3 , Ahmad Khosravi4 , Hossein Amiri Largani5 , Mohammad Bagher Sohrabi6 , Saeed Rashidi1 , Marjan Rashidan6
1- Student Research Committee, Shahroud University of Medical Sciences, Shahroud, Iran
2- Department of Nephrology, Imam Hossain Center for Education, Research and Treatment, Shahroud University of Medical Sciences, Shahroud, Iran ,amerian1060@yahoo.com
3- Department of Sport Physiology, Faculty of Physical Education and Sports Sciences, Shahroud University of Technology, Shahroud, Iran
4- Department of Epidemiology, School of Health, Shahroud University of Medical Sciences, Shahroud, Iran
5- Department of Emergency Medicine, Imam Hossain Center for Education, Research and Treatment, Shahroud University of Medical Sciences, Shahroud, Iran
6- School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran
2- Department of Nephrology, Imam Hossain Center for Education, Research and Treatment, Shahroud University of Medical Sciences, Shahroud, Iran ,
3- Department of Sport Physiology, Faculty of Physical Education and Sports Sciences, Shahroud University of Technology, Shahroud, Iran
4- Department of Epidemiology, School of Health, Shahroud University of Medical Sciences, Shahroud, Iran
5- Department of Emergency Medicine, Imam Hossain Center for Education, Research and Treatment, Shahroud University of Medical Sciences, Shahroud, Iran
6- School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran
Abstract: (80 Views)
Background and Objective: Exercise can affect bone and mineral metabolism, especially calcium and phosphate, as well as parathyroid hormone (PTH) levels in hemodialysis patients. Exercise can increase muscle strength and endurance in dialysis patients and ultimately improve their quality of life. The present study aimed to compare the effects of resistance and aerobic exercise on PTH, calcium, and phosphorus levels in hemodialysis patients.
Materials and Methods: This double-blind clinical trial was conducted in 2024 on 108 hemodialysis patients at Imam Hossein Hospital, Shahroud, Iran. Patients were randomly divided into three equal groups of resistance exercise, aerobic exercise, and control group (36 cases per group). After 16 weeks of standard and specified resistance and aerobic exercise intervention, changes in serum calcium, phosphorus, and PTH of the patients were evaluated. Data were analyzed using SPSS software (version 23) and relevant statistical tests, such as t-test, repeated measures test, and LSD test. In all analyses, a significance level of P<0.05 was considered.
Results: Of the 108 patients studied, 74 (68.1%) were male, and the mean age of the cases was 64.69±16.95 years. During the 16-week intervention period, a significant increase in calcium levels (P=0.033), a significant decrease in phosphorus levels (P=0.038), and PTH (P=0.025) were observed in both exercise intervention groups; however, no significant difference was observed between the two exercise intervention groups.
Conclusion: The results of the present study showed that both resistance and aerobic exercise for at least 60 minutes and three sessions per week can improve bone mineral metabolism in hemodialysis patients. Larger, multicenter studies are needed to investigate the effect of duration and number of exercise sessions on bone mineral disorders.
Materials and Methods: This double-blind clinical trial was conducted in 2024 on 108 hemodialysis patients at Imam Hossein Hospital, Shahroud, Iran. Patients were randomly divided into three equal groups of resistance exercise, aerobic exercise, and control group (36 cases per group). After 16 weeks of standard and specified resistance and aerobic exercise intervention, changes in serum calcium, phosphorus, and PTH of the patients were evaluated. Data were analyzed using SPSS software (version 23) and relevant statistical tests, such as t-test, repeated measures test, and LSD test. In all analyses, a significance level of P<0.05 was considered.
Results: Of the 108 patients studied, 74 (68.1%) were male, and the mean age of the cases was 64.69±16.95 years. During the 16-week intervention period, a significant increase in calcium levels (P=0.033), a significant decrease in phosphorus levels (P=0.038), and PTH (P=0.025) were observed in both exercise intervention groups; however, no significant difference was observed between the two exercise intervention groups.
Conclusion: The results of the present study showed that both resistance and aerobic exercise for at least 60 minutes and three sessions per week can improve bone mineral metabolism in hemodialysis patients. Larger, multicenter studies are needed to investigate the effect of duration and number of exercise sessions on bone mineral disorders.
Type of Study: Original |
Subject:
Nephrology
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