Volume 26, Issue 3 (Avicenna Journal of Clinical Medicine-Autumn 2019)                   Avicenna J Clin Med 2019, 26(3): 151-157 | Back to browse issues page

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Amiri Karladani Z, Shayegh S S, Hakimaneh S M R, Naghizadeh M M, Shokri H, Naeini A. Investigation of the Antifungal Effect of Rosa Damascena Essential Oil and Mixed Mouthwash (Grape Vinegar and Rosa Damascena essential oil) Against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida glabrata. Avicenna J Clin Med 2019; 26 (3) :151-157
URL: http://sjh.umsha.ac.ir/article-1-1941-en.html
Investigation of the Antifungal Effect of Rosa Damascena Essential Oil and Mixed Mouthwash (Grape Vinegar and Rosa Damascena essential oil) Against Candida albicans, Candida dubliniensis, Candida parapsilosis and Candida glabrata
Zahra Amiri Karladani , Seyed Shojaedin Shayegh , Seyed Mohammad Reza Hakimaneh , Mohammad Mahdi Naghizadeh , Hojjatollah Shokri , Alireza Naeini 1
1- , Naeini@shahed.ac.ir
Abstract:   (3962 Views)
Background and Objective: Oral candidiasis is often caused by Candida albicans, followed by C. dubliniensis, C. parapsilosis, and C. glabrata. The present study aimed to investigate the antifungal effects of Rosa damascena (R. damascena) essential oil, mixed mouthwash of R. damascena essential oil and grape vinegar, as well as nystatin against various standard Candida species.
Materials and Methods: This descriptive study was performed on 5 standard strains of various Candida species. The anti-Candida effects of R. damascena and mixed mouthwash against various Candida strains were assessed using well diffusion and broth macrodilution methods. Nystatin was utilized as a positive control drug.
Results: The results of the well diffusion assay of  R. damascena essential oil and mixed mouthwash were 17 and 6 mm regarding C. albicans strains, respectively, and 15 mm and 0 regarding other Candida strains, respectively. With respect to the results obtained from broth macrodilution test, the minimum inhibitory concentration of R. damascena essential oil and mixed mouthwash were found to be 8 and 6 µg/ml, 124 and 12 µg/ml, 31 and 12 µg/ml, as well as 62 and 25 µg/ml for C. albicans, C. dubliniensis, C. glabrata , and C. parapsilosis, respectively. Moreover, C. albicans was the most sensitive Candida species to R. damascena essential oil and the mixed mouthwash.
Conclusion: The results showed that R. damascena essential oil and mixed mouthwash remarkably led to the inhibition of Candida species growth causing oral candidiasis.
Keywords: Grape Vinegar, Oral Candidiasis, Rose Damascena
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Type of Study: Original | Subject: Parasitology & Mycology
References
1. Sharifzadeh A, Khosravi AR, Shokri H, Asadi F, Hajiabdulbaghi M, Ashrafi Tamami I. Oral microflora and their relation to risk factors in HIV+ patients with oropharyngeal candidiasis. J Mycol Med. 2013;23(2):105-12. PMID: 23721997 DOI: 10.1016/j.mycmed.2013.02.001
2. Shokri H. Immunology of fungal infections. 1st ed. Mashhad: Ferdowsi University of Mashhad; 2019. P. 47. [Persian]
3. Zeini F, Mahbod SA, Emami M. Medical mycology. 1st ed. Tehran: University of Tehran; 2012. P. 78-80. [Persian]
4. Khosravi AR, Shokri H, Ziglari T. Fungal diseases in immunocompromised patients. 1st ed. Tehran: Jahade-E-Daneshgahi; 2008. P. 49-50. [Persian]
5. Khosravi AR. Fungal infections and immune responses. 1st ed. Tehran: University of Tehran; 2007. P. 149-51. [Persian]
6. Zarghami M, Farzin D, Bagheri K. Anti depressant effects of Rosa damascena on laboratory rats (A controlled experimental blind study). J Mazandaran Univ Med Sci. 2001;11(33):27-33. [Persian]
7. Das P, Nanda S. Medicinal efficacy of rose plants: a mini review. Pharmatutor. 2015;3(10):23-6.
8. Ramazanalizadeh F, Rabbani M, Khoroshi M, Asghari A. Antimicrobial effect of Rosa damascene and grape vinegar in comparison with herbal Persica mouthwash against oral bacteria in vitro. Dentistry J. 2015;27(2):110-7. [Persian]
9. Budak NH, Aykin E, Seydim AC, Greene AK, Guzel-Seydim ZB. Functional properties of vinegar. J Food Sci. 2014;79(5):R757-64. PMID: 24811350 DOI: 10.1111/1750-3841.12434
10. Naeini A, Shayegh SS, Shokri H, Davati A, Khazaei A, Akbari A. In vitro antifungal effect of herbal mixture (Nigella sativa, Foeniculum vulgare and Camellia sinensis) against Candida species isolated from denture wearers. J Herbmed Pharmacol. 2017;6(2):74-9.
11. Nejad BS, Rajabi M, Mamoudabadi AZ, Zarrin M. In vitro anti-Candida activity of the hydroalcoholic extracts of Heracleum persicum fruit against pathogenic Candida species. Jundishapur J Microbiol. 2014;7(1):e8703. PMID: 25147655 DOI: 10.5812/jjm.8703
12. National Committee for Clinical Laboratory Standards. Reference method for broth dilution antifungal susceptibility testing of yeasts. 2nd ed. PA: Villanova: National Committee for Clinical Laboratory Standards; 2002.
13. Atai Z, Abdollahi H, Naderipour S, Mohammadi S. Comparison of antifungal and antibacterial effects of Persica Matrica and Iralwex with Chlorhexidine mouthwashes (An in vitro study). J Dent Sch Shahid Beheshti Univ Med Sci. 2007;25(1):58-65.
14. Naeini A, Naseri M, Kamalinejad M, Khoshzaban F, Rajabian T, Nami H, et al. Study on Anti_ Candida effects of essential oil and extracts of Iranian medicinal plants, In vitro. J Med Plants. 2011;2(38):163-72. [Persian]
15. Hoseinpour H, Peel SA, Rakhshandeh H, Forouzanfar A, Taheri M, Rajabi O, Saljoghinejad M, et al. Evaluation of Rosa damascena mouthwash in the treatment of recurrent aphthous stomatitis : a randomized, double-blinded, placebo-controlled clinical trial. Quintessence Int. 2011;42(6):483-91. PMID: 21519586
16. Tofighi Z, Molazem M, Doostdar B, Taban P, Shahverdi AR, Samadi N, et al. Antimicrobial activities of three medicinal plants and investigation of flavonoids of Tripleurospermum disciforme. Iran J Pharm Res. 2015;14(1):225-31. PMID: 25561928
17. Shohayeb M, Abdel-Hameed ES, Bazaid SA, Maghrabi I. Antibacterial and antifungal activity of Rosa damascena MILL. essential oil, different extracts of rose petals. GlobalJ Pharmacol. 2014;8(1):1-7. DOI: 10.5829/idosi.gjp.2014.8.1.81275
18. Ataee Bojd MS, Hanafi Bojd R. The evaluation of antimicrobial effects of five different brands of rose water, water extract of Rosa damascene in comparison with rose oil. J Birjand Univ Med Sci. 2014;21(3):292-9. [Persian]
19. Bagheri M, Mahmoudi Rad M, Mansouri A, Younespour S, Taheripanah R. A comparison between antifungal effect of Fumaria officinalis, Echinacea angustifolia, vinegar, and fluconazole against Candida albicans and Candida glabrata isolated from vagina candidiasis. Iran J Obstetrics Gynecol Infertil. 2015;17(136):1-9. [Persian]
20. Rezaie Dastjerdi M, Motevaselian M, Moghadamnia AA, Khafri S, Zuahkiani M, Mahdavi Omran S. The effect of the vinegare plus rose water mouthwash on denture stomatitis candidiasis. J Mazandaran Univ Med Sci. 2014;23(1):187-95. [Persian]
21. Mota AC, de Castro RD, de Araujo Oliveira J, Oliveira Lima E. Antifungal activity of apple cider vinegar on Candida species involved in denture stomatitis. J Prosthodont. 2014;24(4):296-302. PMID: 25219289 DOI: 10.1111/jopr.12207
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