Volume 28, Issue 1 (Avicenna Journal of Clinical Medicine-Spring 2021)                   Avicenna J Clin Med 2021, 28(1): 66-69 | Back to browse issues page


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Alipour M, Khashei Varnamkhasti K, Eslami Moghaddam M, Panahi M. A Case Report of Giant Congenital Melanocytic Nevus. Avicenna J Clin Med. 2021; 28 (1) :66-69
URL: http://sjh.umsha.ac.ir/article-1-2207-en.html
1- PhD Candidate, Department of Genetics, School of Medicine, Kazerun Branch, Islamic Azad University, Kazerun, Iran
2- Instructor, Department of Genetics, School of Medicine, Kazerun Branch, Islamic Azad University, Kazerun, Iran , khalil.khashei2016@gmail.com
3- Gynecologist, Obstetrics and Gynecology Ward, Valiasr Hospital, Kazerun, Iran
4- MSc in Genetics, Obstetrics and Gynecology Ward, Valiasr Hospital, Kazerun, Iran
Abstract:   (329 Views)
Background: Giant congenital melanocytic nevus is caused by intrauterine somatic mutations in the genes involved in the mitogen-activated protein kinase pathway. It is a rare melanocytic lesion with a prevalence of 1 per 20,000 live births occurring at birth or shortly thereafter.
Case Presentation: Here, we presented the case of a term male neonate with giant congenital melanocytic nevus. He was born to a 33-year-old mother. The initial pediatric examination revealed a skin mosaic pattern in his torso. The pigmented and rough skin of this area, along with several prominent wart-shaped lesions and demarcated borders, confirmed the giant congenital melanocytic nevus.
Conclusion: Despite the rarity of this lesion, it is of great importance since it may associate with severe complications, such as malignant melanoma. Therefore, it is necessary to adopt appropriate medical management by recognizing the nature of the lesion.
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Type of Study: Case Report | Subject: Dermatology

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