For  determining   the  incidence  of  hospital  mortality and left ventricular

   function in patients with acute myocardial infarction (AMI) after thrombolytic

   therapy  with  streptokinase  in  Hamadan  Ekbatan  Educational   Hospital  in

   1997, we performed a quasi experimental study according to reference time

   after  onset  of symptoms.  Patients  with  A.MI  were  divided  in  two  groups:

   control group and interference ( streptokinase group ).

      The hospital mortality was 10% and 18%  in interference  and control groups

   respectively.  The  incidence  of  pulmonary edema  and Cardiogenic shock

   (killip class III,IV) was 11% & 4% in interference group respectively , and 16% &

   9% in control group respectively. 

     According   to   the   results  obtained,  the  incidence of  sever MR(+4) and

   ejection fraction (EF) in interference group were 3.5% and  11%  respectively.

     These values for control group were  9%  and  37%  respectively.  The results

   showed  the  improvement  of left  ventricular function in interference group

   due to reperfusion after thrombolytic therapy.