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Showing 2 results for Mehrpooya
The Effect of Education by Pharmacists for Hyperlipidemic Patients Treated With Statins on Patient’s Beliefs About Proper Use of Medications
M Mehrpooya , M Taravati Javad , A Larki , Y Mohammadi , S Ataei , M Kalvandi ,
Volume 24, Issue 1 (Scientific Journal of Hamadan University of Medical Sciences-Spring 2017)
Abstract

Introduction: Hyperlipidemia is one of the most common chronic diseases found in millions of people. Studies have shown that the patient’s adherences to medication instructions provided by the pharmacist or doctor are important, yet unfortunately many patients do not adhere to proper usage of these drugs. The aim of this study was the evaluation of the effect of education by pharmacists for hyperlipidemic patients treated with statins on patient beliefs about the proper use of medications and compliance.

Methods: In this interventional clinical trial study, the studied population was all hospitalized patients with heart disease treated with statins at Hamadan Farshchian hospital from January 2016 to June 2016. The sample size in this study was 50. Information was obtained in relation to each patient, using 2 questionnaires including demographic characteristics and beliefs questionnaire. Data were analyzed using the SPSS.19 software and t test, Mann-Whitney, and X2 tests. Significance level was considered less than 0.05

Results: Statistical test results showed that before the intervention, treatment belief was not significantly different between the 2 groups (P = 0.54), yet after the intervention the treatment belief increased in the intervention group (P = 0.007) and concern about using the drug declined.

Conclusions: These findings suggest that education by pharmacists in patients with hyperlipidemia could have a positive and effective role on their belief about the proper use of drugs. In other words, it could have a role in the control of chronic diseases and could help promote public health.


Effect of Doxycycline on Clinical Outcomes in Patients with Ischemic Stroke
Mojtaba Khazaei, Zahra Aminian, Maryam Mehrpooya, Salman Khazaei,
Volume 31, Issue 2 (Avicenna Journal of Clinical Medicine-Summer 2024)
Abstract
Background and Objective: Stroke is the second leading cause of disability and mortality across the globe. The present study aimed to assess the effect of doxycycline on clinical outcomes of patients with ischemic stroke.
Materials and Methods: In this double-blind clinical trial, 60 patients with ischemic stroke were selected in the first 24 hours of post-stroke and randomly assigned to two groups: intervention and control. In the intervention group, patients received 100 mg of doxycycline every 12 hours for seven days in addition to standard treatments. Both groups were followed up before the intervention, on days 7, 30, and 90 after the treatment in terms of the severity of stroke clinical outcomes using National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Scale (mRS) tests.
Results: The mean age of patients in the intervention and control groups were 68.33±12.15 and 67.40±9.99 years (P>0.05). No significant difference was observed between the intervention and control groups in terms of NIHSS and mRS scores at baseline and on the seventh day. Nonetheless, in the intervention group, the NIHSS score on days 30 (P=0.007) and 90 (P<0.001), as well as the mRS score on days 30 (P=0.009) and 90 (P<0.01) was significantly less than the control group.
Conclusion: In ischemic stroke, the administration of doxycycline 100 mg every 12 hours for seven days is safe, reduces neurological disorders, and improves the clinical outcome of patients within one to three months after the treatment.
 
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