Volume 29, Issue 1 (Avicenna Journal of Clinical Medicine-Spring 2022)                   Avicenna J Clin Med 2022, 29(1): 12-17 | Back to browse issues page

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Gharebaghi N, Valizade Hasanloei M A, Fromandi M, Pashaei M R. Neutrophil-to-Albumin Ratio as A Novel Predictor of Mortality in Patients with Sepsis. Avicenna J Clin Med 2022; 29 (1) :12-17
URL: http://sjh.umsha.ac.ir/article-1-2313-en.html
1- Department of Infectious Diseases, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
2- Department of Anesthesiology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
3- Urmia University of Medical Sciences, Urmia, Iran
4- Department of internal medicine, School of Medicine, Patient Safety Research Center, Clinical Research Institute, Urmia University of Medical Science, Urmia, Iran , dr.pashaei@yahoo.com
Abstract:   (922 Views)
Background and Objective: Sepsis is a syndrome involving physiological, pathological, and biochemical abnormalities caused by infection. Very few studies have been performed to evaluate the prognostic value of the neutrophil-to-albumin ratio. The present study aimed to evaluate the neutrophil-to-albumin ratio in patients with sepsis admitted to the intensive care unit (ICU).
Materials and Methods: All patients admitted to the ICU with a diagnosis of sepsis were included in the study. The inclusion criteria entailed the age range of ≥18 years, having sepsis, and hospitalization in the ICU for more than two weeks.
Results: A total of 75 patients with a mean age of 72.34 years were evaluated, and 57.8% of cases died. There was a significant difference between neutrophils on the second and third days between deceased and discharged patients. The neutrophil-to-albumin ratio at the time of admission, the second day, and the third day were 31.62, 33.36, and 34.31, respectively; nonetheless, no significant difference was observed between the deceased and discharged (P>0.05).
Conclusion: As evidenced by the results of this study, the neutrophil-to-albumin ratio in deceased patients was higher than that in discharged ones; however, this difference was not statistically significant. Moreover, neutrophil percentage, duration of mechanical ventilation, and duration of hospitalization in deceased patients were significantly higher, as compared to those in discharged patients.
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Type of Study: Original | Subject: Infectious Diseases

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