Volume 32, Issue 4 (Avicenna Journal of Clinical Medicine-Winter 2026)
Avicenna J Clin Med 2026, 32(4): 218-225 |
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Emad Momtaz H, Kazemi Najafabadi H, Pirdehghan A. Assessment of Response to Treatment in Children with Urolithiasis. Avicenna J Clin Med 2026; 32 (4) :218-225
URL: http://sjh.umsha.ac.ir/article-1-2863-en.html
URL: http://sjh.umsha.ac.ir/article-1-2863-en.html
1- Department of Pediatrics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran , momtaz@umsha.ac.ir
2- Department of Pediatrics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
3- School of Public Health and Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran
2- Department of Pediatrics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
3- School of Public Health and Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran
Abstract: (85 Views)
Background and Objective: The diagnosis and treatment of urinary system stones are highly crucial, especially in children due to the lack of specific symptoms, risks, and possible complications. Therefore, this study was conducted to investigate the response rate to drug treatment in children with ureteral stones.
Materials and Methods: In this descriptive-cross-sectional study, 298 children with urolithiasis who were referred to the Children's Kidney Clinic (Hamadan University of Medical Sciences) were reviewed. Demographic and clinical information of the patients was extracted from their records and recorded in checklists designed for each patient, then compared using chi-square and t-test analytical statistics. Data were analyzed using SPSS software (version 24) at the significance level. (P<0.05)
Results: Of the 298 children under the age of 3 years with urinary tract stones, 48.3% were boys and 51.7% were girls. Regarding the prevalence of clinical symptoms, 35% of the patients were asymptomatic, and hematuria (18.5%) was the most common symptom. The most significant risk factor reported was a family history (64.8%). Hyperuricosuria was the most common metabolic disorder, and hydronephrosis was the most significant associated problem among the patients. The results of statistical analyses showed a statistically significant relationship between stone size and symptoms of the disease, number of stones, metabolic disorders, concomitant problems, medication used, type of surgery, number of surgeries, number of stone recurrences, and drug treatment results.
Conclusion: The majority of children with stones smaller than 5 mm responded well to drug treatment, and the recurrence of stones was less in these patients. In the present study, patients with stones larger than 5 mm responded less to drug treatment and subsequently required more surgery, especially more invasive surgeries.
Materials and Methods: In this descriptive-cross-sectional study, 298 children with urolithiasis who were referred to the Children's Kidney Clinic (Hamadan University of Medical Sciences) were reviewed. Demographic and clinical information of the patients was extracted from their records and recorded in checklists designed for each patient, then compared using chi-square and t-test analytical statistics. Data were analyzed using SPSS software (version 24) at the significance level. (P<0.05)
Results: Of the 298 children under the age of 3 years with urinary tract stones, 48.3% were boys and 51.7% were girls. Regarding the prevalence of clinical symptoms, 35% of the patients were asymptomatic, and hematuria (18.5%) was the most common symptom. The most significant risk factor reported was a family history (64.8%). Hyperuricosuria was the most common metabolic disorder, and hydronephrosis was the most significant associated problem among the patients. The results of statistical analyses showed a statistically significant relationship between stone size and symptoms of the disease, number of stones, metabolic disorders, concomitant problems, medication used, type of surgery, number of surgeries, number of stone recurrences, and drug treatment results.
Conclusion: The majority of children with stones smaller than 5 mm responded well to drug treatment, and the recurrence of stones was less in these patients. In the present study, patients with stones larger than 5 mm responded less to drug treatment and subsequently required more surgery, especially more invasive surgeries.
Type of Study: Original |
Subject:
Pediatrics (all specialties)
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