Volume 25, Issue 4 (Avicenna Journal of Clinical Medicine-Winter 2019)                   Avicenna J Clin Med 2019, 25(4): 236-243 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Abbasi M, Moradi F, Esna-Ashari F, Seifrabiei M A. Epidemiological and Pathological Study of Lung Cancer in Patients Referred to Ekbatan and Shahid Beheshti Hospitals in Hamadan during 2001 - 2016. Avicenna J Clin Med 2019; 25 (4) :236-243
URL: http://sjh.umsha.ac.ir/article-1-1830-en.html
1- , esna_f@yahoo.com
Abstract:   (3928 Views)
Background and Objective: Lung cancer is one of the most common types of cancer and the main reason of cancer-caused mortality in Iran. The awareness of cancer epidemiologic and pathologic characteristics helps to prevent the prevalence and incidence of cancer.
Materials and Methods: This comparative descriptive study was conducted on patients with lung cancer referring to Ekbatan and Shahid Beheshti Hospitals during 2001-2016. Risk factors as well as clinical and demographic data were collected from medical records.
Results: The mean age of the patients was 61.11 ±12.23 years and 166 patients (83%) were male. A total number of 120 (66.7%) patients lived in urban areas. The frequency of patients who had a positive history for consumption of opioid, industrial drugs, cigarette, and hookah were 2%, 0%, 42.2%, and 1%, respectively. The most common symptoms were cough and dyspnea.  The time interval between the appearance of clinical signs and diagnosis was 5.32 months. The most common paraneoplastic symptom was bone pain (45.5%), and the most frequent pathologic form was squamous cell carcinoma (33.5%). The right upper lobe (27.5%) and left upper lobe (23.5%) were the most common lobes.
Conclusion: Since the time interval between clinical signs and diagnosis was long and squamous cell carcinoma was the most common type of cancer, it is important to control risk factors, specifically smoking, to  prevent cancer.
 
Full-Text [PDF 371 kb]   (1620 Downloads)    
Type of Study: Original | Subject: Hematology & Oncology

References
1. Siegel R, Ward E, Brawley O. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin. 2011;61(4):212–36. PMID: 21685461 DOI: 10.3322/caac.20121
2. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61(2):69–90. PMID: 21296855 DOI: 10.3322/caac.20107
3. International Early Lung Cancer Action Program Investigators, Henschke CI, Yankelevitz DF, Libby DM, Pasmantier MW, Smith JP, et al. Survival of patients with stage I lung cancer detected on CT screening. N Engl J Med. 2006;355(17):1763-71. PMID: 17065637 DOI: 10.1056/ NEJMoa060476
4. Didkowska J, Wojciechowska U, Mañczuk M, Łobaszewski J. Lung cancer epidemiology: contemporary and future challenges worldwide. Ann Transl Med. 2016;4(8): 150. PMID: 27195268 DOI: 10.21037/atm.2016.03.11
5. Brawley OW. Avoidable cancer deaths globally. CA Cancer J Clin. 2011;61(2):67-8. PMID: 21296854 DOI: 10.3322/caac.20108
6. Ghobadi H, Sharghi A, Sadat-Kermani J. Epidemiology and risk factors for lung cancer in Ardabil, Iran. J Ardabil Univ Med Sci. 2013;13(2):220-8. [Persian]
7. Ferketich AK, Niland JC, Mamet R, Zornosa C, D'Amico TA, Ettinger DS, et al. Smoking status and survival in the national comprehensive cancer network non-small cell lung cancer cohort. Cancer. 2013;119(4):847-53. PMID: 23023590 DOI: 10.1002/cncr.27824
8. Minna J, Schiller JH. Harrison’s principles of internal medicine. 17th ed. New York: McGraw-Hill; 2008.
9. Shroff GS, Viswanathan C, Carter BW, Benveniste MF, Truong MT, Sabloff BS. Staging lung cancer: metastasis. Radiol Clin North Am. 2018;56(3):411-8. PMID: 29622076 DOI: 10.1016/j.rcl.2018.01.009
10. Chen WQ, Zuo TT, Zheng RS, Zeng HM, Zhang SW, He J. Lung cancer incidence and mortality in China in 2013. Zhonghua Zhong Liu Za Zhi. 2017;39(10):795-800. PMID: 29061027 DOI: 10.3760/cma.j.issn.0253-3766.2017.10.015
11. Radziszewska A, Karczmarek-Borowska B, Gradalska-Lampart M, Filip AA. Epidemiology, prevention and risk morbidity factors for lung cancer. Pol Merkur Lekarski. 2015;38(224):113-8. PMID: 25771522
12. Dela Cruz CS, Tanoue LT, Matthay RA. Lung cancer: epidemiology, etiology, and prevention. Clin Chest Med. 2011;32(4):605-44. PMID: 22054876 DOI: 10.1016/j.ccm. 2011.09.001
13. Kristeleit H, Enting D, Lai R. Basic science of lung cancer. Eur J Cance. 2011;47(Suppl 3):S19-21. PMID: 21943998 DOI: 10.1016/S0959-8049(11)70186-1
14. Almasi H, Farahmand M, Hassanzadeh J, Raei M. The trend of lung cancer incidence rate based on Fars province cancer registery data, 2001-2008. Payesh. 2012;11(4):477-83. [Persian]
15. Doll R, Hill AB. Smoking and carcinoma of the lung; preliminary report. Br Med J. 1950;2(4682):739-48. PMID: 14772469
16. Najafi F, Jafari R, Mozafari HR, Leghaei Z. Trend in lung cancer incidence in Kermanshah province-Iran. J Kermanshah Univ Med Sci. 2011;14(4):342-348. [Persian]
17. Pallis AG, Syrigos KN. Lung cancer in never smokers: disease characteristics and risk factors. Crit Rev Oncol Hematol. 2013;88(3):494-503. PMID: 23921082 DOI: 10.1016/j.critrevonc.2013.06.011
18. Ehteshami Afshar A, Moosavi MA, Aram N, Deldar M, Raiisi S, Goharzad Ataie M, et al. Determination of frequency of histopathologic types of primary lung neoplasms in those patients admitted in tehran hospitals. Razi J Med Sci. 2002;8(26):373-9. [Persian]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Avicenna Journal of Clinical Medicine

Designed & Developed by : Yektaweb