Volume 28, Issue 3 (Avicenna Journal of Clinical Medicine-Autumn 2021)
Avicenna J Clin Med 2021, 28(3): 145-150 |
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Akbarzadeh S, Bazzazi N, Sobhan M. Comparison of Choroidal Thickness in Psoriasis and Control Groups Using Optical Coherence Tomography. Avicenna J Clin Med 2021; 28 (3) :145-150
URL: http://sjh.umsha.ac.ir/article-1-2301-en.html
URL: http://sjh.umsha.ac.ir/article-1-2301-en.html
Comparison of Choroidal Thickness in Psoriasis and Control Groups Using Optical Coherence Tomography
1- Associate Professor, Department of Ophthalmology, School of Medicine, Hamadan University of Medical Sciences
2- Assistant Professor, Department of Dermatology, School of Medicine, Psoriasis Research Center, Hamadan University of Medical Sciences , mreza_sobhan@yahoo.com
2- Assistant Professor, Department of Dermatology, School of Medicine, Psoriasis Research Center, Hamadan University of Medical Sciences , mreza_sobhan@yahoo.com
Abstract: (1565 Views)
Background and Objective: One of the most common extracutaneous complications in psoriasis patients is ocular complications, which is controversial concerning its effect on choroidal thickness. This study aimed to compare the psoriasis patients with healthy individuals in terms of the thickness of the choroidal layer using the optical coherence tomography technique.
Materials and Methods: In this case-control study, 30 psoriasis patients were compared with 32 healthy individuals who were matched for gender and age. Choroidal thickness was measured in both groups using the optical coherence tomography technique. Furthermore, the relationship of the choroidal thickness with the severity and duration of the disease was assessed in patients.
Results: The mean choroidal thickness of the left eye (312.1±12.0 mµ vs. 296.3±20.8 mµ), right eye (310.6±12.5mµ vs. 297.5±17.5mµ), and regardless of the left or right eye (311.3±12.2 mµ vs. 296.9±19.1mµ) was significantly higher in patients, compared to the control group (P=0.001 for all three mean values). No significant relationship was found between disease duration and severity with choroid thickness. Moreover, the patients with multiple limb involvement had a higher mean choroid thickness; however, it was not statistically significant.
Conclusion: According to the results of the present study, patients with psoriasis have a greater choroidal thickness, compared to healthy individuals, which is not related to the severity, type of involvement, and duration of the disease.
Materials and Methods: In this case-control study, 30 psoriasis patients were compared with 32 healthy individuals who were matched for gender and age. Choroidal thickness was measured in both groups using the optical coherence tomography technique. Furthermore, the relationship of the choroidal thickness with the severity and duration of the disease was assessed in patients.
Results: The mean choroidal thickness of the left eye (312.1±12.0 mµ vs. 296.3±20.8 mµ), right eye (310.6±12.5mµ vs. 297.5±17.5mµ), and regardless of the left or right eye (311.3±12.2 mµ vs. 296.9±19.1mµ) was significantly higher in patients, compared to the control group (P=0.001 for all three mean values). No significant relationship was found between disease duration and severity with choroid thickness. Moreover, the patients with multiple limb involvement had a higher mean choroid thickness; however, it was not statistically significant.
Conclusion: According to the results of the present study, patients with psoriasis have a greater choroidal thickness, compared to healthy individuals, which is not related to the severity, type of involvement, and duration of the disease.
Type of Study: Original |
Subject:
Ophthalmology (all specialties)
Extended Abstract [HTML 23 KB] (84 Download)
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