Volume 30, Issue 1 (Avicenna Journal of Clinical Medicine-Spring 2023)                   Avicenna J Clin Med 2023, 30(1): 38-44 | Back to browse issues page


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Jamshidi M, Alirezaei P, Mohammadi Pasand F, Mousivand Z. Evaluation of Some Effective Factors in Response to Cryotherapy in Women with Condyloma Acuminata. Avicenna J Clin Med 2023; 30 (1) :38-44
URL: http://sjh.umsha.ac.ir/article-1-2658-en.html
1- Department of Dermatology. School of Medicine, Sina Research Center, Hamadan University of Medical Sciences, Hamadan, Iran
2- Department of Dermatology. School of Medicine, Sina Research Center, Hamadan University of Medical Sciences, Hamadan, Iran , dr.fatemeh.mohammadipasnad@gmail.com
3- Farabi Laboratory, Hamadan, Iran
Abstract:   (678 Views)
Background and Objective: Condyloma acuminata is treated in different ways, each of which may have advantages and disadvantages. The present study aimed to evaluate the effective factors in response to cryotherapy treatment in women with condyloma acuminata.
Materials and Methods: This case-control study was conducted on 200 women with condyloma acuminata who were candidates for cryotherapy and were referred to Farshchian Hospital (Sinai) in 2021-2022. Before starting cryotherapy, a biopsy sample was taken from the lesions to perform a polymerase chain reaction (PCR) and determine the genotype of the human papillomavirus. Based on the extracted subtype, the lesions were classified into three high-risk, medium- and low-risk groups. Cryotherapy was performed for each lesion once every two weeks and up to six sessions at most. Patients were examined one month after the last cryotherapy session in terms of recovery with no recovery. Non-response to treatment was considered the case group, and response was regarded as the control group.
Results: In terms of genotype, 43% were high risk, 24.5% were intermediate, and 32.5% were low risk. The frequency of response to treatment was 37%. A response to cryotherapy of condyloma acuminata in the anogenital area of participating showed a significant correlation with age (P=0.008), lesion size (P=0.001), duration of disease (P=0.001), genotype (P=0.001), and lesion location (P =0.014).
Conclusion: Response to cryotherapy treatment in anogenital condyloma acuminata warts is relatively low. Lesions in the vaginal area, younger age, the smaller size of lesions, and shorter duration of infection had a better prognosis after cryotherapy
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Type of Study: Original | Subject: Dermatology

References
1. Yuan H, Li R, Lv J, Yi G, Sun X, Zhao N, et al. Epidemiology of human papillomavirus on condyloma acuminatum in Shandong Province,China. Hum Vaccin Immunother. 2023;19(1):2170662. PMID: 36919446 DOI: 10.1080/21645515.2023.2170662
2. Hirth J. Disparities in HPV vaccination rates and HPV prevalence in the United States: a review of the literature. Hum Vaccin Immunother. 2019;15(1):146-55. PMID: 30148974 DOI: 10.1080/21645515.2018.1512453
3. Chang KC, Chen YC, Ding DC. Condyloma acuminatum mimicking cervical cancer in a pregnant woman and treatment with cryotherapy: A case report. Medicine. 2022;101(49):e32273. PMID: 36626521 DOI: 10.1097/MD.0000000000032273
4. Clanner-Engelshofen BM, Marsela E, Engelsberger N, Guertler A, Schauber J, French LE, et al. Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options. Heliyon. 2020;6(3):e03547. PMID: 32190761 DOI: 10.1016/j.heliyon.2020.e03547
5. Yin G, Zhang Y, Liu J, Wang P, Li X. Successful application of aminolevulinic acid/photodynamic therapy in the treatment of condyloma acuminatum in a young child. Photodiagnosis Photodyn Ther. 2022;38:102746. PMID: 35123017 DOI: 10.1016/j.pdpdt.2022.102746
6. Omahsan L, Zerrouki N, Bazouti S, Zizi N, Dikhaye S. Condyloma acuminata. Rev Prat. 2018;68(4):406.
7. Mistrangelo M, Dal Conte I, Volpatto S, DI Benedetto G, Testa V, Currado F, et al. Current treatments for anal condylomata acuminata. Minerva Chir. 2018;73(1):100-6. PMID: 29154519 DOI: 10.23736/S0026-4733.17.07554-X
8. Mawardi P, Febrianto B, Yuliarto D, Sumandjar T. Comparing the efficacy of chemical cautery to cryosurgery on CD4+ status of HIV patients with Condyloma Acuminata. Clin Cosmet Investig Dermatol. 2021;14:1453-8. PMID: 34675581 DOI: 10.2147/CCID.S328667
9. Zhan M, Tong Z, Chen S, Miao Y, Yang Y. Establishing a prediction model for recurrence of condyloma acuminatum. Eur J Med Res. 2022;27(1):183. PMID: 36138469 DOI: 10.1186/s40001-022-00816-7
10. Hogendoorn GK, Bruggink SC, de Koning MN, Eekhof JA, Hermans KE, Rissmann R, et al. Morphological characteristics and human papillomavirus genotype predict the treatment response in cutaneous warts. Br J Dermatol. 2018;178(1):253-60. PMID: 28646591 DOI: 10.1111/bjd.15758
11. Rasi A, Soltani-Arabshahi R, Khatami A. Cryotherapy for anogenital warts: factors affecting therapeutic response. Dermatol Online J. 2007;13(4):2. PMID: 18318999
12. Kim DY, Park HS, Cho S, Yoon HS. Factors determining treatment response to cryotherapy for foot warts. Ann Dermatol. 2019;31(4):457-60. PMID: 33911628 DOI: 10.5021/ad.2019.31.4.457
13. Sharma N, Sharma S, Singhal C. A comparative study of liquid nitrogen cryotherapy as monotherapy versus in combination with podophyllin in the treatment of condyloma acuminata. J Clin Diagn Res. 2017;11(3):1-5. PMID: 28511487 DOI: 10.7860/JCDR/2017/23797.9339
14. Khaled A, Romdhane B, Kharfi M, Zeglaoui F, Fazaa B, Kamoun MR. Assessment of cryotherapy by liquid nitrogen in the treatment of hand and feet warts. Tunis Med. 2009;87(10):690-2. PMID: 20187359
15. Ahmed I, Agarwal S, Ilchyshyn A, Charles‐Holmes S, Berth‐Jones J. Liquid nitrogen cryotherapy of common warts: cryo‐spray vs. cotton wool bud. Br J Dermatol. 2001;144(5):1006-9. PMID: 11359389 DOI: 10.1046/j.1365-2133.2001.04190.x
16. Tomson N, Sterling J, Ahmed I, Hague J, Berth‐Jones J. Human papillomavirus typing of warts and response to cryotherapy. J Eur Acad Dermatol Venereol. 2011;25(9):1108-11. PMID: 21812829 DOI: 10.1111/j.1468-3083.2010.03906.x

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