Volume 32, Issue 3 (Avicenna Journal of Clinical Medicine-Autumn 2025)
Avicenna J Clin Med 2025, 32(3): 180-188 |
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Ghofleh Maramazi H, Sharififard M, Saki Malehi A, Mahmoodi Sourestani M, Maraghi E, Jahanifard E et al . Comparison of the Effectiveness of Fennel Essential Oil Shampoo versus 1% Permethrin Shampoo for Pediculus capitis Control. Avicenna J Clin Med 2025; 32 (3) :180-188
URL: http://sjh.umsha.ac.ir/article-1-3239-en.html
URL: http://sjh.umsha.ac.ir/article-1-3239-en.html
Hoda Ghofleh Maramazi1 
, Mona Sharififard1 , Amal Saki Malehi2 , Mohammad Mahmoodi Sourestani3 , Elham Maraghi2 , Elham Jahanifard4 , Sima Rasaei5
, Mona Sharififard1 , Amal Saki Malehi2 , Mohammad Mahmoodi Sourestani3 , Elham Maraghi2 , Elham Jahanifard4 , Sima Rasaei5
1- Department of Vector Biology and Disease Control, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2- Department of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3- Department of Horticultural Sciences, Faculty of Agriculture, Shahid Chamran University of Ahvaz, Ahvaz, Iran
4- Department of Vector Biology and Disease Control, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran ,elham.jahani56@gmail.com
5- Department of Dermatology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2- Department of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3- Department of Horticultural Sciences, Faculty of Agriculture, Shahid Chamran University of Ahvaz, Ahvaz, Iran
4- Department of Vector Biology and Disease Control, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran ,
5- Department of Dermatology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Abstract: (45 Views)
Background and Objective: Pediculus capitis are obligate human ectoparasites, and severe itching is their primary clinical manifestation. This study aimed to evaluate the effectiveness of a fennel essential oil shampoo compared with 1% permethrin shampoo in the treatment of head lice (Pediculosis capitis).
Materials and Methods: In this clinical trial, the per-protocol method and permuted block randomization were employed. In the groups using baby shampoo, 15% fennel, and 1% permethrin, 48, 33, and 43 female students aged 7-11 years were assigned, respectively. After using shampoo, volunteers in all three groups were examined on days 1, 7, and 14 post-treatment to determine the improvement rate (reduction in nits, nymphs, and adult lice). The chi-square test was used for data analysis, and a significance level of P<0.05 was considered significant.
Results: On the first day, the improvement rates for the control, fennel, and permethrin shampoos were 4.9%, 22.6%, and 15.4%, respectively. On day 7, the overall improvement percentages for the control, fennel, and permethrin shampoos were 8.3%, 9.1%, and 20.9%, respectively. On day 14, follow-up with volunteers showed improvements in all three groups: control, fennel shampoo, and permethrin, with rates of 6.5%, 4%, and 13.9%, respectively. On days 1, 7, and 14 after administration, no significant difference was observed among the groups. In the assessment of reduced infestation on day 14, the results showed an 84% improvement in the patient's condition with fennel shampoo, showing a significant difference among the groups.
Conclusion: The rate of improvement among infected individuals using permethrin shampoo was higher on day 14 than among those using the other two shampoos. However, the fennel essential oil shampoo resulted in significantly lower infestation than the baby shampoo and 1% permethrin shampoo.
Materials and Methods: In this clinical trial, the per-protocol method and permuted block randomization were employed. In the groups using baby shampoo, 15% fennel, and 1% permethrin, 48, 33, and 43 female students aged 7-11 years were assigned, respectively. After using shampoo, volunteers in all three groups were examined on days 1, 7, and 14 post-treatment to determine the improvement rate (reduction in nits, nymphs, and adult lice). The chi-square test was used for data analysis, and a significance level of P<0.05 was considered significant.
Results: On the first day, the improvement rates for the control, fennel, and permethrin shampoos were 4.9%, 22.6%, and 15.4%, respectively. On day 7, the overall improvement percentages for the control, fennel, and permethrin shampoos were 8.3%, 9.1%, and 20.9%, respectively. On day 14, follow-up with volunteers showed improvements in all three groups: control, fennel shampoo, and permethrin, with rates of 6.5%, 4%, and 13.9%, respectively. On days 1, 7, and 14 after administration, no significant difference was observed among the groups. In the assessment of reduced infestation on day 14, the results showed an 84% improvement in the patient's condition with fennel shampoo, showing a significant difference among the groups.
Conclusion: The rate of improvement among infected individuals using permethrin shampoo was higher on day 14 than among those using the other two shampoos. However, the fennel essential oil shampoo resulted in significantly lower infestation than the baby shampoo and 1% permethrin shampoo.
Type of Study: Original |
Subject:
Parasitology & Mycology
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