Volume 12, Issue 2 (Scientific Journal of Hamadan University of Medical Sciences-Summer 2005)                   Avicenna J Clin Med 2005, 12(2): 68-71 | Back to browse issues page

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Mazdeh M. A Case Report of Vasculitis Necrotizing after Interferon beta-1b Injection in Multiple Sclerosis. Avicenna J Clin Med 2005; 12 (2) :68-71
URL: http://sjh.umsha.ac.ir/article-1-552-en.html
, m_mazdeh@hotmail.com
Abstract:   (4503 Views)

Introduction : There are several introduced forms of treatment for patients with relapse-remitting & secondary progressive multiple sclerosis in recent years. Interferon beta-1b (Betaferon) is the first of these agents that administered subcutaneously once in every two days.

Case Report: This report is related to a 33 years old female. After 6 times of Betaferon injection vasculitis necrotizing was occurred with perforated ulcer (3´3.5 cm) on the Lt side prox. lower limb . Simultaneoulsly ulcer (0.5´0.5 cm) on the Lt side prox. upper limb , small ulcer (1´1 cm) on the Rt side prox. lower limb and erythemia on the Rt side prox. upper limb around injection site.

Conclusion: Betaferon was stopped to ensure ulcers is healed. The patient showed improvement after 3 months without debridment. It is recommended to proceed with the above plan until complete recovery is achieved.

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Type of Study: Case Report | Subject: Other Clinical Specialties

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