This study assesses the antimicrobial effect of chloroformic extract of
garlic (Allicin) on strains of mycobacterium tuberculosis.
A standard H37RV isolate and isolates from patients with drug resistant
pulmonary tuberculosis were used. A strain sensitive to 4 drugs (rifampin,
isoniazid, ethambutol, and streptomycin), resistant to the four drugs, resistant
to two drugs, and a strain resistant to one drug, were used. The antimicrobial
effect was tested invitro with minimum inhibitory concentrations of the
chloroformic extract of garlic on the mycobacteria.
Middel Broke 7H10 agar medium with 1:128 dilution or 1mg/ml
concentrations of chloroformic extract of garlic were used.
Our study showed that garlic extract is effective in inhibiting growth of
not only drug sensitive, but also drug resistant isolates of mycobacterium
tuberculosis .
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