Introduction: Leukocyte adhesion deficiency type 1 is a rare disorder of function of neutrophils which presents with recurrent bacterial and fungal infections. The patients usually have a history of delayed umbilical cord detachment.

Case Report: The patient was a fourteen-month-old boy with recurrent bronchopneumonia, skin abscess and oral candidiasis. There was a history of abscess formation in site of vaccine injection in two and four months of age. The umbilical cord detachment was occurred in the 6^th day of birth. Laboratory studies showed marked leukocytosis and neutrophilia .Flowcytometry showed low amount of CD18. These were all compatible with a diagnosis of leukocyte adhesion deficiency type I (LADs1).

Conclusions: The patients die in the event of a delay in diagnosis because of recurrent severe infections. Early diagnosis and treatment of these diseases by stem cell transplantation improve the survival of the patient.

(Sci J Hamadan Univ Med Sci 2016; 23 (1):88-92)