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Background and Objective: Chronic obstructive pulmonary disease (COPD) is a worldwide health problem with increasing prevalence. It is often associated with negative health outcomes, including depression. Therefore, the aim of this study was to determine the prevalence of depression in patients with COPD.
Materials and Methods: This cross-sectional study with a descriptive-analytic design was conducted on 103 patients referring to the respiratory disease clinic and admitted to the pulmonary disease department of Shahid Beheshti teaching Hospital, Hamadan, Iran from April to September 2018. The inclusion criteria were the diagnosis of severe and very severe COPD according to the medical history, physical examination, and standard spirometric methods. The patients with lack of bereavement, trauma, and the use of antidepressant drugs were excluded from the study. Depression levels were measured using 21-items Beck II depression questionnaire.
Results: The results of the study showed that 57 patients (55.3%) were males and 46 cases (44.7%) were females. The majority of the subjects (33%) were  in the age group of 50-59 years old. According to the results, the prevalence of depression in the study population was 66%. There was a significant relationship between spirometric parameters of forced expiratory flow at 25-75% of the pulmonary volume, forced expiratory volume at 1 second and COPD severity (P=0.024, P=0.003).
Conclusion: With regard to the high prevalence of depression among people with severe and very severe COPD, it is necessary to consider psychological counseling for patients

Keywords: Chronic Obstructive Pulmonary Disease, Depression, Epidemiology

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