This was a descriptive – analytic study. Sample was 60 thalasemic school aged children (Case group) and 60 healthy school-aged children (Control group). For sampling, four blood transfusion canters were selected by randomized stratified sampling. Then thalassemic children were chosen by poisson sampling. Between the school of thalassemic children, nine school were selected by randomized sampling. Then healthy children  group was chosen by simple sampling. Data was gathered by a questionnaire. Outcome showed that self-Esteem and social competence of thalassemic school aged were significantly lower and their behavior problem were higher than healthy ones. So that, the psycho-social development of thalassmic school-aged children were lower than school-aged children.