Volume 27, Issue 4 (Avicenna Journal of Clinical Medicine-Winter 2021)                   Avicenna J Clin Med 2021, 27(4): 226-231 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Bazzazi N, Sharafi Zamir M, Akbarzadeh S, Mohammadi Y, Ahmadpanah M. Prevalence of Depression in Patients with Diabetic Retinopathy. Avicenna J Clin Med 2021; 27 (4) :226-231
URL: http://sjh.umsha.ac.ir/article-1-2146-en.html
1- Associate Professor, Department of Ophthalmology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
2- General Practitioner, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
3- Associate Professor, Department of Epidemiology, School of Health, Hamadan University of Medical Sciences, Hamadan, Iran
4- Associate Professor, Department of Ophthalmology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran , m1ahmad2000@gmail.com
Abstract:   (1875 Views)
Background and Objective:Diabetic retinopathy is one of the most important and debilitating complications of diabetes with an increasing prevalence in most countries. It has a dramatic effect on people's quality of life and increases the symptoms of anxiety and depression in patients with diabetes. Therefore, the present study aimed to determine the prevalence of depression in patients with diabetic retinopathy.
Materials and Methods:This descriptive/ cross-sectional study was conducted on 245 patients with retinopathy referred to the ophthalmology clinic of Farshchian Hospital in Hamadan during 2019- 2020. They were selected via available and consecutive sampling method and were evaluated for depression with the 21-item Beck questionnaire. Data were analyzed in SPSS software (version 16) at a 95% confidence level.
Results:The mean scores of patients' age and duration of diabetes were reported as 54.47± 8.5 and 8.5 ± 4.15 years, respectively. In terms of gender, the majority of participants (58.7%) were female. The prevalence of depression in patients with diabetic retinopathy was obtained at 49.8% and in proliferative and non-proliferative retinopathy were 68.2% and 43%, respectively (P<0.001). The prevalence rates of depression in men and women were reported as 45.9% and 51.5% (P=0.428). Moreover, in patients treated with insulin and without insulin, the prevalence rates of depression were obtained at 50.4% and 49.2% (P=0.846). The correlation coefficients of depressive disorder with age and duration of diabetes were calculated at 0.123 (P=0.054) and 0.369 (P<0.001), respectively.
Conclusion:Depression is one of the most serious problems in patients with diabetic retinopathy. As evidenced by the results of the present study, the prevalence ofdepression is significantly correlated with the severity of retinopathy and duration of diabetes.
Full-Text [PDF 833 kb]   (887 Downloads)    
Type of Study: Original | Subject: Clinical Psychology

References
1. Stratton I, Kohner E, Aldington S, Turner R, Holman R, Manley S, et al. UKPDS 50: risk factors for incidence and progression of retinopathy in type II diabetes over 6 years from diagnosis. Diabetologia. 2001;44(2):156-63.PMID: 11270671DOI: 10.1007/s001250051594
2. Antwi-Bafour S, Hammond S,Adjei JK, Kyeremeh R, Martin-Odoom A, Ekem I. A case–control study of prevalence of anemia among patients with type 2 diabetes. J Med Case Rep. 2016;10(1):110.PMID: 27142617DOI: 10.1186/s13256-016-0889-4
3. Gedebjerg A, Almdal TP, Berencsi K, Rungby J, Nielsen JS, Witte DR, et al.Prevalence of micro-and macrovascular diabetes complications at time of type 2 diabetes diagnosis and associated clinical characteristics: a cross-sectional baseline study of 6958 patients in the Danish DD2 cohort. J Diabetes Complications. 2018;32(1):34-40.PMID: 29107454DOI: 10.1016/j.jdiacomp.2017.09.010
4. Rees G, Xie J, Fenwick EK, Sturrock BA, Finger R, Rogers SL, et al. Association between diabetes-related eye complications and symptoms of anxiety and depression. JAMA Ophthalmol. 2016;134(9):1007-14.PMID: 27387297DOI: 10.1001/jamaophthalmol.2016.2213
5. Kobrin Klein BE. Overview of epidemiologic studies of diabetic retinopathy. Ophthalmic Epidemiol. 2007;14(4):179-83.PMID: 17896294DOI: 10.1080/09286580701396720
6. Romero-Aroca P. Managing diabetic macular edema: the leading cause of diabetes blindness. World J Diabetes. 2011;2(6):98-104. PMID: 21860693DOI: 10.4239/wjd.v2.i6.98
7. Lee R, Wong TY, Sabanayagam C. Epidemiology of diabetic retinopathy, diabetic macular edema and related vision loss. Eye Vis(Lond). 2015;2:17.PMID: 26605370DOI: 10.1186/s40662-015-0026-2
8. Lamoureux EL, Tai ES, Thumboo J, Kawasaki R, Saw SM, Mitchell P, et al. Impact of diabetic retinopathy on vision-specific function. Ophthalmology. 2010;117(4):757-65.PMID: 20122736DOI: 10.1016/j.ophtha.2009.09.035
9. Mohammadnezhad R, Azmodeh M, Tabatabaee S, Hosseini Nasab S. Comparison of active memory, inhibition of response and dimensions of nature and character in patients with type 2 diabetic retinopathy and normal counterparts in Tabriz. Armaghane Danesh. 2020;25(2):368-80. [Persian]
10. Noroozinejad GH, Boustani H, Neamat PS, Behrouzian F. Comparison of depression among diabetic and non-diabetic patients. Jundishapur Sci Med J. 2006;5(1):385-91.
11. Grandinetti A, Kaholokula JK, Crabbe KM, Kenui CK, Chen R, Chang HK. Relationshipbetween depressive symptoms and diabetes among native Hawaiians. Psychoneuroen-docrinology. 2000;25(3):239-46.PMID: 10737695DOI: 10.1016/s0306-4530(99)00047-5
12. Bădescu S, Tătaru C, Kobylinska L, Georgescu E, Zahiu D, Zăgrean A, et al. The association between diabetes mellitus and depression. J Med Life. 2016;9(2):120-5.PMID: 27453739
13. Chen X, Lu L. Depression in diabetic retinopathy: a review and recommendation for psychiatric management. Psychosomatics. 2016;57(5):465-71.PMID: 27380941DOI: 10.1016/j.psym.2016.04.003
14. Salinero-Fort MA, Gómez-Campelo P, San Andrés-Rebollo FJ, Cárdenas-Valladolid J, Abánades-Herranz JC, Carrillo de Santa Pau E, et al. Prevalence of depression in patients with type 2 diabetes mellitus in Spain (the DIADEMA Study): results from the MADIABETES cohort. BMJ Open. 2018;8(9):e020768.PMID: 30249627DOI: 10.1136/bmjopen-2017-020768
15. Olson D, Le P, Vu T, Van Buren E, Lin FC, Zhang A. Association between anxiety, depression, and severity of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2020;61(7):3836. DOI: 10.1167/iovs.18-26108
16. Ahmed M, Gad M, Al-Adlany M. Cognitive impairment and depression in patients with diabetic retinopathy. Egypt J Psychiatry. 2020;41(1):1.DOI: 10.4103/ejpsy.ejpsy_13_19
17. Bao Y, Cope S, Gaddis M, Drees B. Prevalence and predictors of depression in patients with diabetic retinopathy in a nationally representative sample. Invest Ophthalmol Vis Sci. 2020;61(7):1902.
18. Abu Ameerh MA, Hamad GI. The prevalence of depressive symptoms and related risk factors among diabetic patients with retinopathy attending the Jordan University Hospital. Eur J Ophthalmol. 2020;22:1120672120912691.PMID: 32202144DOI: 10.1177/1120672120912691
19. Urrutia-Aliano D, Segura ER. Depressive symptoms and type 2 diabetes mellitus in outpatients of an Armed Forces hospital in Lima, Peru, 2012: a cross-sectional study. Medwave. 2016;16(3):e6435. PMID: 27144926DOI: 10.5867/medwave.2016.03.6435
20. Hirai FE, Tielsch JM, Klein BE, Klein R. Relationship between retinopathy severity, visual impairment and depression in persons with long-term type1 diabetes. Ophthalmic Epidemiol. 2012;19(4):196-203.PMID: 22775274DOI:10.3109/09286586.2012.692006
21. Larijani B, Bayat M, Gorgani M, Bandarian F, Akhondzade S, Sadjadi S. Association between depression and diabetes. German J Psychiatry. 2004;7(3):62-5.
22. Roy MS, Roy A, Affouf M. Depression is a risk factor for poor glycemic control and retinopathy in African-Americans with type 1 diabetes. Psychosom Med. 2007;69(6):537-42. PMID: 17634567DOI: 10.1097/PSY.0b013e3180df84e2
23. Sieu N, Katon W, Lin EH, Russo J, Ludman E, Ciechanowski P. Depression and incident diabetic retinopathy: a prospective cohort study. Gen Hosp Psychiatry. 2011;33(5):429-35. PMID: 21762993DOI: 10.1016/j.genhosppsych.2011.05.021

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Avicenna Journal of Clinical Medicine

Designed & Developed by : Yektaweb