Maxillomandibular fixation (MMF) method is performed in maxillary or
mandibular fractures , plastic surgeries and congenitally anomaly of
mandibular. Post operative nausea and vomiting due to anesthesia and
opioids is one of the most important complications. This study performed for
determination of metoclopramide and metoclopramid plus dexamethasone
effects for reduction of nausea and vomiting after maxillomandibular
fixation surgery in the patients with mandibular fractures.
In this double-blind clinical trial , 60 patients candidated to
maxillomandibular fixation surgery were randomized into two treating
groups(A: Metoclopramide alone, B: Metoclopramide + Dexamethasone )
and evaluated in nausea and vomiting rates after operation. The patients
were followed in three stages in the operation room , in recovery room , and
in the ward upto 24 hours.
In first stage , 30% of patients in group A and 6% of patients in group B
encountered post operative nausea and vomiting. During second stage ,
these rates were 17% in group A and zero for group B. Non of the patients
in both groups , encountered post operative nausea and vomiting in third
stage of following.
The findings indicate that combination of metoclopramide and
dexamethasone can decrease post operative nausea and vomiting
incidence rates effectively. Suitable tolerance of patients to drug and less
complications of dexamethasone compared risk of post operative vomiting
are more factors that account for complication therapy with
dexamethasone and other antiemetic agents. However , expand use of this
method needs more studied.
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