Volume 10, Number 1 (Scientific Journal of Hamadan University of Medical Sciences-Spring 2003)                   Sci J Hamadan Univ Med Sci 2003, 10(1): 5-11 | Back to browse issues page


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Ghaffari S M A, Moshtaghi S A A. The Effect of Indium on Intestinal Absorption of Iron Using Everted Gut Sac Method. Sci J Hamadan Univ Med Sci . 2003; 10 (1) :5-11
URL: http://sjh.umsha.ac.ir/article-1-677-en.html

Abstract:   (605 Views)

Iron is an essential metal which involves in more cell activities in the form of enzymes and / or other metaloproteins . Indium is one of the toxic elements that may be interfered with iron metabolism . Using this element has increased recently by different industry.

          Therefore the aim of this investigation was to study interfer of indium on first phase of iron metabolism (absorption intestinal ) by everted gut sac (E.G.S) .

          Preliminary results showed that the optimum concentration of iron and indium for best intestinal absorption were 102 and 70 mg/L , respectively . Addition of glucose to incubation media caused increase in iron and / or indium absorption and reduction was seen where ouabain was added to the media , suggest a probable active transport of the element across of the intestinal mucosal cell . Iron absorption was reduced almost by 28%
   when indium was presented in incubation media .

          Results obtained from this study indicated that indium might be able to interfer with iron metabolism , at intestinal absorption .

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Type of Study: Original | Subject: Special

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